IFNAR2 anticorps (AA 165-260)

N° du produit ABIN721825

Détail du produit anti-IFNAR2 anticorps

Antigène: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Épitope: AA 165-260

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFNAR2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Rat

Homologie: Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse IFNAR2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-IFNAR2 (ABIN721825)

Lopušná, Benkóczka, Lupták, Matúšková, Lukáčiková, Ovečková, Režuchová: "Murine gammaherpesvirus targets type I IFN receptor but not type III IFN receptor early in infection." dans: Cytokine, Vol. 83, pp. 158-70, (2016) (PubMed).

Détails sur IFNAR2

Antigène: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Autre désignation: IFNAR2 (IFNAR2 Produits)

Synonymes: anticorps AI747302, anticorps Ifnar-2, anticorps IFN-R, anticorps IFN-alpha-REC, anticorps IFNABR, anticorps IFNARB, anticorps IFN-R-2, anticorps IFNBR, anticorps interferon alpha and beta receptor subunit 2, anticorps interferon (alpha and beta) receptor 2, anticorps IFNAR2, anticorps Ifnar2

Sujet:

Synonyms: Ifnar-2, AI747302, Interferon alpha/beta receptor 2, IFN-R-2, IFN-alpha/beta receptor 2, Type I interferon receptor 2, Ifnar2

Background: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation. Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1. Isoform 2 and 3 may be potent inhibitors of type I IFN receptor activity (By similarity).

ID gène: 15976

UniProt: O35664

Pathways: Signalistation JAK/STAT, Hepatitis C