RCAN2 anticorps (AA 1-100)

N° du produit ABIN721915

Détail du produit anti-RCAN2 anticorps

Antigène: RCAN2 (Regulator of Calcineurin 2 (RCAN2))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RCAN2 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RCAN2

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RCAN2

Antigène: RCAN2 (Regulator of Calcineurin 2 (RCAN2))

Autre désignation: RCAN2 (RCAN2 Produits)

Synonymes: anticorps DSCR1L1, anticorps si:ch211-124g24.1, anticorps zgc:85746, anticorps RCAN2, anticorps DKFZp459H071, anticorps rcan2, anticorps CSP2, anticorps MCIP2, anticorps RCN2, anticorps ZAKI-4, anticorps ZAKI4, anticorps Csp2, anticorps Dscr1l1, anticorps Dcip2, anticorps Zaki-4, anticorps regulator of calcineurin 2, anticorps rcan2, anticorps RCAN2, anticorps Rcan2

Sujet:

Synonyms: Calcipressin 2, Calcipressin-2, CSP2, Down syndrome candidate region 1-like 1, Down syndrome critical region gene 1 like 1 protein, MCIP2, Myocyte enriched calcineurin interacting protein 2, Myocyte-enriched calcineurin-interacting protein 2, RCAN2, RCAN2_HUMAN, RCN2, Regulator of calcineurin 2, Thyroid hormone responsive protein ZAKI4, Thyroid hormone-responsive protein ZAKI-4, ZAKI4.

Background: Calcineurin is a Ca(2+) dependent protein phosphatase that is involed in several neuornal functions. Proteins belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFATs (Nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. Calcipressin-2, also known as RCAN2 and DSCR1L1 (Down syndrome candidate region 1-like 1), is a 197 amino acid protein that is highly expressed in both the cytoplasm and nucleus of neurons and is the only RCAN family member that is found in glial cells. Calcipressin-3, also known as RCAN3 and DSCR1L2 (Down syndrome candidate region 1-like protein 2), is a 241 amino acid protein that potentially is involved in central nervous system development. Calcipressin-3 interacts with cardiac troponin I, suggesting that it may play a role in cardiac contraction events.

ID gène: 10231