Amphiregulin anticorps
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- Antigène Voir toutes Amphiregulin (AREG) Anticorps
- Amphiregulin (AREG)
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Amphiregulin est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF)
- Fonction
- Amphiregulin antibody
- Purification
- Protein A purified
- Immunogène
- recombinant human Amphiregulin
- Top Product
- Discover our top product AREG Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- PBS
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
- Date de péremption
- 24 months
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- Antigène
- Amphiregulin (AREG)
- Autre désignation
- Amphiregulin (AREG Produits)
- Sujet
- AREG, AR, SDGF, AREGB, CRDGF,Amphiregulin is an EGF related growth factor that signals through the EGF/TGF-a receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin's extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant human Amphiregulin is a 11.3 kDa glycoprotein consisting of 98 amino acid residues.
- ID gène
- 374
- NCBI Accession
- NM_001657, NP_001648
- UniProt
- P15514
- Pathways
- Signalisation RTK, EGFR Signaling Pathway
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