Amphiregulin anticorps

N° du produit ABIN7539230

Détail du produit anti-Amphiregulin anticorps

Antigène: Amphiregulin (AREG)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Amphiregulin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Fonction: Amphiregulin antibody

Purification: Protein A purified

Immunogène: recombinant human Amphiregulin

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Stock: 4 °C,-20 °C

Stockage commentaire: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Date de péremption: 24 months

Détails sur Amphiregulin

Antigène: Amphiregulin (AREG)

Autre désignation: Amphiregulin (AREG Produits)

Synonymes: anticorps AR, anticorps CRDGF, anticorps SDGF, anticorps Sdgf, anticorps AREG, anticorps AREGB, anticorps AREG/SDGF, anticorps amphiregulin, anticorps AREG, anticorps Areg

Sujet: AREG, AR, SDGF, AREGB, CRDGF,Amphiregulin is an EGF related growth factor that signals through the EGF/TGF-a receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin's extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant human Amphiregulin is a 11.3 kDa glycoprotein consisting of 98 amino acid residues.

ID gène: 374

NCBI Accession: NM_001657, NP_001648

UniProt: P15514

Pathways: Signalisation RTK, EGFR Signaling Pathway