DCLK2 anticorps (AA 652-766)

N° du produit ABIN7539736

Détail du produit anti-DCLK2 anticorps

Antigène: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Épitope: AA 652-766

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DCLK2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Fonction: DCLK2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human DCLK2 (AA: 652-766) expressed in mammalian.

Clone: 3H1G4

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur DCLK2

Antigène: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Autre désignation: DCLK2 (DCLK2 Produits)

Synonymes: anticorps CL2, anticorps CLICK-II, anticorps CLICK2, anticorps CLIK2, anticorps DCAMKL2, anticorps DCDC3, anticorps DCDC3B, anticorps DCK2, anticorps 6330415M09Rik, anticorps AU044875, anticorps Click-II, anticorps Dcamkl2, anticorps DCLK2, anticorps cb572, anticorps dclk, anticorps sb:cb572, anticorps si:dkey-180n16.1, anticorps Dck2, anticorps RGD1308384, anticorps doublecortin like kinase 2, anticorps doublecortin-like kinase 2, anticorps doublecortin-like kinase 2a, anticorps DCLK2, anticorps Dclk2, anticorps dclk2a

Sujet:

Description: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.

Aliases: CL2, DCK2, CLIK2, DCDC3, CLICK2, DCDC3B, DCAMKL2, CLICK-II

Poids moléculaire: 83.6 kDa

ID gène: 166614

UniProt: Q8N568