Cytochrome C anticorps (AA 51-105)

N° du produit ABIN723590

Détail du produit anti-Cytochrome C anticorps

Antigène: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Épitope: AA 51-105

Reactivité: Humain, Rat, Souris, Lapin, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cytochrome C est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))

Réactivité croisée: Poulet, Humain, Souris, Lapin, Rat

Homologie: Cow,Pig,Horse,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Cytochrome C

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Cytochrome C (ABIN723590)

Liu, Chen, Du, Wu, Dong, Qu, Fan, Yao: "GluR3B Ab's induced oligodendrocyte precursor cells excitotoxicity via mitochondrial dysfunction." dans: Brain research bulletin, Vol. 130, pp. 60-66, (2017) (PubMed).

Abdel-Hamid, El-Azab, Moustafa: "Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model." dans: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 390, Issue 4, pp. 379-395, (2017) (PubMed).

Tian, Wang, Zhang, Luo, Jiang, Zhang, Mei, Wu, Wu, Peng, Long, Luo, Guo: "Phosphoprotein Gene Contributes to the Enhanced Apoptosis Induced by Wild-Type Rabies Virus GD-SH-01 In Vitro." dans: Frontiers in microbiology, Vol. 8, pp. 1697, (2017) (PubMed).

Gu, Chen, Jiang, Zhang: "ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction underlie apoptosis induced by resveratrol and arsenic trioxide in A549 cells." dans: Chemico-biological interactions, Vol. 245, pp. 100-9, (2016) (PubMed).

Duan, Li, Li, Xing, Zhang, Li, Zhao, Sun, Gao, Li et al.: "Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic ..." dans: Free radical biology & medicine, Vol. 94, pp. 74-87, (2016) (PubMed).

Zhang, He, Guo, Li, Wang, Yang, Cui: "Sulfiredoxin-1 protects against simulated ischaemia/reperfusion injury in cardiomyocyte by inhibiting PI3K/AKT-regulated mitochondrial apoptotic pathways." dans: Bioscience reports, Vol. 36, Issue 2, (2016) (PubMed).

Gu, Chen, Jiang, Zhang: "Resveratrol Synergistically Triggers Apoptotic Cell Death with Arsenic Trioxide via Oxidative Stress in Human Lung Adenocarcinoma A549 Cells." dans: Biological trace element research, Vol. 163, Issue 1-2, pp. 112-23, (2015) (PubMed).

Gao, Yu, Yan, Li, Shen, Jia, Guan, Gao, Kan: "Poly (ADP?ribose) polymerase? and cytochrome c?mediated apoptosis induces hepatocyte injury in a rat model of hyperammonia?induced hepatic failure." dans: Molecular medicine reports, (2015) (PubMed).

Li, Li, Sun, Ni, Chen, Guo, Chen: "Increased Expression of Mitochondrial Inner-Membrane Protein Mpv17 After Intracerebral Hemorrhage in Adult Rats." dans: Neurochemical research, Vol. 40, Issue 8, pp. 1620-30, (2015) (PubMed).

Chen, Gu, Jiang, Zhang: "Nuclear translocation of nuclear factor kappa B is regulated by G protein signaling pathway in arsenite-induced apoptosis in HBE cell line." dans: Environmental toxicology, (2015) (PubMed).

Ye, Wu, Li, Li, Zheng, Liu, Ye: "Millimeter Wave Treatment Inhibits Apoptosis of Chondrocytes via Regulation Dynamic Equilibrium of Intracellular Free Ca (2+)." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 464161, (2015) (PubMed).

Zhang, Ma, Qi, Wei, Zhang, Li, Chiu: "P62 regulates resveratrol-mediated Fas/Cav-1 complex formation and transition from autophagy to apoptosis." dans: Oncotarget, Vol. 6, Issue 2, pp. 789-801, (2015) (PubMed).

Jiang, Ren, Jiang, Wang, Zhang, Yin, Wang, Qi, Wang, Feng: "Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis." dans: Neuroscience, Vol. 277, pp. 132-8, (2014) (PubMed).

Chen, Jiang, Lai, Liu, Zhang: "Resveratrol protects against arsenic trioxide-induced oxidative damage through maintenance of glutathione homeostasis and inhibition of apoptotic progression." dans: Environmental and molecular mutagenesis, (2014) (PubMed).

Fang, Zhang, Qi, Fan, Luo, Liu, Tan: "Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells." dans: PLoS ONE, Vol. 9, Issue 12, pp. e115204, (2014) (PubMed).

Liao, Li, Li, Liu: "Organellar proteome analyses of ricin toxin-treated HeLa cells." dans: Toxicology and industrial health, (2014) (PubMed).

Wang, Wang, Shan, Song, Dai, Wang, Chi: "Mu-calpain mediates hippocampal neuron death in rats after lithium-pilocarpine-induced status epilepticus." dans: Brain research bulletin, Vol. 76, Issue 1-2, pp. 90-6, (2008) (PubMed).

Détails sur Cytochrome C

Antigène: Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))

Autre désignation: Cytochrome C (CYCS Produits)

Synonymes: anticorps CYC, anticorps HCS, anticorps THC4, anticorps cyct, anticorps cyc, anticorps hcs, anticorps CYCS, anticorps cytc, anticorps CYCSA, anticorps CG17903, anticorps Cyt C, anticorps Cyt c, anticorps Cyt-c2, anticorps CytC-2, anticorps Cytc, anticorps Cytc-p, anticorps DC4, anticorps DMc01, anticorps Dmel\\CG17903, anticorps cyt c, anticorps cyt c-p, anticorps cyt-c-p, anticorps cyt-c2, anticorps cyt.c, anticorps cytochrome c, anticorps dc4, anticorps pDMc01, anticorps wu:fk52b01, anticorps zgc:86706, anticorps ENSMUSG00000058927, anticorps cytochrome c, somatic, anticorps cytochrome c, somatic S homeolog, anticorps Cytochrome c proximal, anticorps cytochrome c, somatic b, anticorps cytochrome c, somatic pseudogene, anticorps cytochrome c-like, anticorps cytochrome c, anticorps CYCS, anticorps cycs.S, anticorps cycs, anticorps Cycs, anticorps Cyt-c-p, anticorps cycsb, anticorps Gm10053, anticorps LOC100724240, anticorps CYC, anticorps LOC100847700, anticorps LOC101107954, anticorps LOC106829744, anticorps LOC106992390, anticorps LOC102085712

Sujet:

Synonyms: CYC, HCS, THC4, Cytochrome c, CYCS

Background: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

ID gène: 54205

UniProt: P99999

Pathways: Apoptose, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity