TGFB1 anticorps (AA 351-390)

N° du produit ABIN724685

Détail du produit anti-TGFB1 anticorps

Antigène: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Épitope: AA 351-390

Reactivité: Humain, Souris, Rat, Mouton, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGFB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Lapin, Rat, Mouton

Homologie: Dog,Cow,Pig,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TGF-Beta 1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-TGFB1 (ABIN724685)

Shang, Liu, Liu, Li, Dou, Zhang, Sun, Zhang, Zhu, Mu, Ding, Wen: "Telmisartan improves vascular remodeling through ameliorating prooxidant and profibrotic mechanisms in hypertension via the involvement of transforming growth factor-β1." dans: Molecular medicine reports, Vol. 16, Issue 4, pp. 4537-4544, (2018) (PubMed).

Mao, Zhang, Qi, Jiang, Wu, Lu, Ainiwaer, Shang, Xu, Hao, Shou, Li, Li, Zhang, Bao, Wen: "Efficacy of radiotherapy for the treatment of cystic echinococcosis in naturally infected sheep." dans: Infectious diseases of poverty, Vol. 6, Issue 1, pp. 88, (2017) (PubMed).

Shen, Wu, Wang, Zhao, Zhang, Li, Zhao: "Chloroquine attenuates paraquat-induced lung injury in mice by altering inflammation, oxidative stress and fibrosis." dans: International immunopharmacology, Vol. 46, pp. 16-22, (2017) (PubMed).

Eren, Turgut, Akin, Demir: "The Suppression of Wound Healing Response with Sirolimus and Sunitinib Following Experimental Trabeculectomy in a Rabbit Model." dans: Current eye research, Vol. 41, Issue 3, pp. 367-76, (2016) (PubMed).

Xue, Chen, Zhao, Zhao, Duan, Zheng: "The Overexpression of TGF-β and CCN2 in Intrauterine Adhesions Involves the NF-κB Signaling Pathway." dans: PLoS ONE, Vol. 10, Issue 12, pp. e0146159, (2016) (PubMed).

Venter, Marques, Santos, Monte-Alto-Costa: "Use of platelet-rich plasma in deep second- and third-degree burns." dans: Burns : journal of the International Society for Burn Injuries, Vol. 42, Issue 4, pp. 807-14, (2016) (PubMed).

Ganguly, Wen, Myer, Czech, Sahu, Steinmetz, Raman: "Anti-atherogenic effect of trivalent chromium-loaded CPMV nanoparticles in human aortic smooth muscle cells under hyperglycemic conditions in vitro." dans: Nanoscale, Vol. 8, Issue 12, pp. 6542-54, (2016) (PubMed).

Zhu, Hu, Yu, Ren, Hu: "High Molecular Weight Hyaluronic Acid Inhibits Fibrosis of Endometrium." dans: Medical science monitor : international medical journal of experimental and clinical research, Vol. 22, pp. 3438-3445, (2016) (PubMed).

Du, Niu, Wang, Zhao, Kong, Zhang, Nan: "TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." dans: Molecular medicine reports, Vol. 13, Issue 3, pp. 2159-66, (2016) (PubMed).

Shang, Liu, Liu, Zhang, Mu, Zhu, Liang, Zhai, Ding, Li, Wen: "Acetyl-11-Keto-β-Boswellic Acid Attenuates Prooxidant and Profibrotic Mechanisms Involving Transforming Growth Factor-β1, and Improves Vascular Remodeling in Spontaneously Hypertensive Rats." dans: Scientific reports, Vol. 6, pp. 39809, (2016) (PubMed).

Tang, Jiang, Zhou, Xia, Dai: "Increased adenosine levels contribute to ischemic kidney fibrosis in the unilateral ureteral obstruction model." dans: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 737-743, (2015) (PubMed).

Hu, Zeng, Jiang, Hu, Meng, Zhu, Mao: "The expression of marker for endometrial stem cell and fibrosis was increased in intrauterine adhesious." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 2, pp. 1525-34, (2015) (PubMed).

Sun, Li, Wen, Wang, Ji, Ma: "Immunological effect induced by mesenchymal stem cells in a rat liver transplantation model." dans: Experimental and therapeutic medicine, Vol. 10, Issue 2, pp. 401-406, (2015) (PubMed).

Abdelmagid, Belcher, Moussa, Lababidi, Sondag, Novak, Sanyurah, Frara, Razmpour, Del Carpio-Cano, Safadi: "Mutation in osteoactivin decreases bone formation in vivo and osteoblast differentiation in vitro." dans: The American journal of pathology, Vol. 184, Issue 3, pp. 697-713, (2014) (PubMed).

Erbas, Yapislar, Oltulu, Yavaso?lu, Aktug, Taskiran: "Nephro-protective effect of granulocyte colony-stimulating factor in streptozotocin induced diabetic rats." dans: Biotechnic & histochemistry : official publication of the Biological Stain Commission, Vol. 89, Issue 7, pp. 488-96, (2014) (PubMed).

Kou, Hu, Yao, Wang, Shen, Kang, Hong: "Transforming growth factor-?1 promotes Treg commitment in nasal polyposis after intranasal steroid treatment." dans: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 62, Issue 3, pp. 283-9, (2013) (PubMed).

Détails sur TGFB1

Antigène: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Autre désignation: TGF beta 1 (TGFB1 Produits)

Synonymes: anticorps CED, anticorps DPD1, anticorps LAP, anticorps TGFB, anticorps TGFbeta, anticorps TGF-beta, anticorps TGF-BETA-1, anticorps TGF-beta5, anticorps ced, anticorps dpd1, anticorps lap, anticorps tgf-beta, anticorps tgfb, anticorps tgfb5, anticorps tgfbeta, anticorps TGF-beta1, anticorps TGFbeta1, anticorps Tgfb, anticorps Tgfb-1, anticorps ai39657, anticorps tgfb1, anticorps wu:fb13a07, anticorps xx:ai39657, anticorps TGFB1, anticorps csd, anticorps cdb1, anticorps cdg2, anticorps csd1, anticorps csd2, anticorps csd3, anticorps ebmd, anticorps lcd1, anticorps bigh3, anticorps cdgg1, anticorps betaig-h3, anticorps TGFB4, anticorps transforming growth factor beta 1, anticorps transforming growth factor beta-1, anticorps transforming growth factor beta 1 L homeolog, anticorps transforming growth factor, beta 1, anticorps transforming growth factor, beta 1a, anticorps transforming growth factor beta induced L homeolog, anticorps TGFB1, anticorps Tgfb1, anticorps tgfb1.L, anticorps tgfb1a, anticorps tgfbi.L

Sujet:

Synonyms: CED, DPD1, TGFB, TGFbeta, Transforming growth factor beta-1, TGF-beta-1, TGFB1

Background: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

Poids moléculaire: 12.8kDa

ID gène: 7040

UniProt: P01137

Pathways: EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints