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Cyclin C anticorps (AA 23-100)

CCNC Reactivité: Humain WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN727250
  • Antigène Voir toutes Cyclin C (CCNC) Anticorps
    Cyclin C (CCNC)
    Épitope
    • 23
    • 14
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-100
    Reactivité
    • 62
    • 31
    • 29
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 61
    • 1
    Lapin
    Clonalité
    • 62
    Polyclonal
    Conjugué
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Cyclin C est non-conjugé
    Application
    • 51
    • 25
    • 25
    • 20
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain
    Homologie
    Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Cyclin C
    Isotype
    IgG
    Top Product
    Discover our top product CCNC Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Cyclin C (CCNC)
    Autre désignation
    Cyclin C (CCNC Produits)
    Synonymes
    anticorps CG1C_DROME, anticorps CG7281, anticorps CYCC, anticorps Cln3, anticorps Cyc-C, anticorps DmcycC, anticorps Dmel\\CG7281, anticorps SRB11, anticorps cycC, anticorps cyclinC, anticorps dTRAP33, anticorps fj11d06, anticorps wu:fj11d06, anticorps zgc:73078, anticorps Cyclin-C, anticorps CycC, anticorps AI451004, anticorps AU020987, anticorps CG1C, anticorps Cyclin C, anticorps cyclin C, anticorps cyclin C L homeolog, anticorps cyclin-C, anticorps CycC, anticorps ccnc, anticorps CCNC, anticorps Ccnc, anticorps ccnc.L, anticorps LOC5577815
    Sujet

    Synonyms: CycC, Cyclin-C, SRB11 homolog, hSRB11, CCNC

    Background: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.

    ID gène
    892
    UniProt
    P24863
    Pathways
    Cycle Cellulaire, Regulation of Lipid Metabolism by PPARalpha
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