FGL2 anticorps (AA 75-150)

N° du produit ABIN727785

Détail du produit anti-FGL2 anticorps

Antigène: FGL2 (Fibrinogen-Like 2 (FGL2))

Épitope: AA 75-150

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGL2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from rat FGL2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-FGL2 (ABIN727785)

Yang, Fujikado, Kolodin, Benoist, Mathis: "Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance." dans: Science (New York, N.Y.), Vol. 348, Issue 6234, pp. 589-94, (2015) (PubMed).

Détails sur FGL2

Antigène: FGL2 (Fibrinogen-Like 2 (FGL2))

Autre désignation: FGL2 (FGL2 Produits)

Synonymes: anticorps FGL2, anticorps wu:fj83c10, anticorps zgc:136619, anticorps si:ch211-276e22.3, anticorps fibroleukin, anticorps T49, anticorps pT49, anticorps AI385601, anticorps musfiblp, anticorps fibrinogen like 2, anticorps fibrinogen like 2 L homeolog, anticorps fibrinogen-like 2a, anticorps fibrinogen-like 2, anticorps fibrinogen-like protein 2, anticorps FGL2, anticorps fgl2.L, anticorps fgl2a, anticorps Fgl2

Sujet:

Synonyms: Fibroleukin, Cytotoxic T-lymphocyte-specic protein, Fibrinogen-like protein 2, Fibrinogen like protein 2, Prothrombinase, Fibroleukin, pT49, T49, G3V7P2_RAT, Fibrinogen-like 2.

Background: FGL2 is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. It may play a role in physiologic functions at mucosal sites. It is constitutively expressed in cytotoxic T-cells. Lack of expression in other lymphoid- and nonlymphoid-derived cell lines suggested that expression of FGL2 may be restricted to lymphocytes. FGL2 is induced via a mechanism involving IFNG and components of the IFNG signaling pathway, including STAT1 and IRF1.

ID gène: 84586

UniProt: G3V7P2