CGRP anticorps (AA 65-130)

N° du produit ABIN728218

Cet anticorps Lapin Polyclonal détecte spécifiquement CGRP dans ELISA, WB, IHC (p), IF (cc), IF (p) et IHC (fro). Il présente une réactivité avec des échantillons de Humain et Rat. Il a été cité dans 7+ publications.

Aperçu rapide pour CGRP anticorps (AA 65-130) (ABIN728218)

Antigène: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CGRP est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CGRP anticorps

Épitope: AA 65-130

Réactivité croisée: Humain, Rat

Homologie: Mouse,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CALCA

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CGRP (ABIN728218)

He, Xiong, Liu, He, Feng, Shang, Xia, Wang, Qiu, Luo, Liu, Wang: "MicroRNA-127 targeting of mitoNEET inhibits neurite outgrowth, induces cell apoptosis and contributes to physiological dysfunction after spinal cord transection." dans: Scientific reports, Vol. 6, pp. 35205, (2016) (PubMed).

Liu, Peng, Long, Li, Ke, Fang: "Mutual effect between neuropeptides and inflammatory cytokines in neurogenic SMSCs of human temporomandibular joint." dans: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 4, pp. 602-7, (2014) (PubMed).

Wang, Sun, Tang, Guo, Zhou, Chen, Shen: "Basic fibroblast growth factor attenuates the degeneration of injured spinal cord motor endplates." dans: Neural regeneration research, Vol. 8, Issue 24, pp. 2213-24, (2014) (PubMed).

Tu, Li, Peng, Hu, Liu, Kong, Liu, Gao, Xu, Xu, Qiu, Fan, Zhu, Yu, Zheng, Wu, Peng, Song, Wu, Liang: "P2X(7) inhibition in stellate ganglia prevents the increased sympathoexcitatory reflex via sensory-sympathetic coupling induced by myocardial ischemic injury." dans: Brain research bulletin, Vol. 96, pp. 71-85, (2013) (PubMed).

Liu, Li, Peng, Tu, Kong, Liu, Gao, Xu, Qiu, Fan, Zhu, Yu, Zheng, Wu, Peng, Song, Wu, Li, Liang: "Sensory-sympathetic coupling in superior cervical ganglia after myocardial ischemic injury facilitates sympathoexcitatory action via P2X7 receptor." dans: Purinergic signalling, Vol. 9, Issue 3, pp. 463-79, (2013) (PubMed).

Li, Zhang, Zhang, Ma: "The protective effect of genistein postconditioning on hypoxia/reoxygenation-induced injury in human gastric epithelial cells." dans: Acta pharmacologica Sinica, Vol. 30, Issue 5, pp. 576-81, (2009) (PubMed).

Détails sur CGRP

Antigène: CGRP (CALCA) (Calcitonin-Related Polypeptide alpha (CALCA))

Autre désignation: CGRP

Sujet:

Synonyms: CAL6, CGRP, Cal1, Calc, RATCAL6, calcitonin, Calcitonin gene-related peptide 1, Alpha-type CGRP, Calcitonin gene-related peptide I, CGRP-I, Calca

Background: CGRP induces vasodilation. It dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role.

ID gène: 24241

UniProt: P06881

Pathways: Hormone Activity, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, Feeding Behaviour