PAR1 anticorps (AA 251-350)

N° du produit ABIN728743

Détail du produit anti-PAR1 anticorps

Antigène: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Épitope: AA 251-350

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PAR1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-PAR1 (ABIN728743)

Posthuma, Posma, Schep, Bender, van Oerle, van der Wal, Ten Cate, Spronk: "Protease-activated receptors are potential regulators in the development of arterial endofibrosis in high-performance athletes." dans: Journal of vascular surgery, Vol. 69, Issue 4, pp. 1243-1250, (2019) (PubMed).

Ben Shimon, Zeimer, Shavit Stein, Artan-Furman, Harnof, Chapman, Eisenkraft, Pick, Maggio: "Recovery from trauma induced amnesia correlates with normalization of thrombin activity in the mouse hippocampus." dans: PLoS ONE, Vol. 12, Issue 11, pp. e0188524, (2017) (PubMed).

Fan, Chen, Ni, Wang, Sun, Chen, Zheng: "Expression of MMP-1/PAR-1 and patterns of invasion in oral squamous cell carcinoma as potential prognostic markers." dans: OncoTargets and therapy, Vol. 8, pp. 1619-26, (2015) (PubMed).

Acton, Miles: "Stimulation of Glia Reveals Modulation of Mammalian Spinal Motor Networks by Adenosine." dans: PLoS ONE, Vol. 10, Issue 8, pp. e0134488, (2015) (PubMed).

Liu, Xie, Luo, Chen, Zhou, Xia, Chen, Zhou, Cao, Cao, Zhou: "Identification of FLOT2 as a novel target for microRNA-34a in melanoma." dans: Journal of cancer research and clinical oncology, (2014) (PubMed).

Détails sur PAR1

Antigène: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Autre désignation: Thrombin receptor (F2R Produits)

Synonymes: anticorps CF2R, anticorps HTR, anticorps PAR-1, anticorps PAR1, anticorps TR, anticorps Par1, anticorps TRGPC, anticorps AI482343, anticorps Cf2r, anticorps ThrR, anticorps Par-1, anticorps f2r-a, anticorps par1, anticorps coagulation factor II thrombin receptor, anticorps coagulation factor II (thrombin) receptor, anticorps coagulation factor 2 (thrombin) receptor L homeolog, anticorps F2R, anticorps F2r, anticorps f2r.L

Sujet:

Synonyms: TR, HTR, CF2R, PAR1, PAR-1, Proteinase-activated receptor 1, Coagulation factor II receptor, Thrombin receptor, F2R

Background: High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

ID gène: 2149

UniProt: P25116

Pathways: Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus