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DTNBP1 anticorps (AA 101-200)

DTNBP1 Reactivité: Rat ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN731363
  • Antigène Voir toutes DTNBP1 Anticorps
    DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
    Épitope
    • 14
    • 9
    • 8
    • 7
    • 7
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reactivité
    • 59
    • 28
    • 26
    • 15
    • 1
    • 1
    Rat
    Hôte
    • 88
    • 2
    Lapin
    Clonalité
    • 88
    • 2
    Polyclonal
    Conjugué
    • 26
    • 9
    • 9
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DTNBP1 est non-conjugé
    Application
    • 47
    • 42
    • 30
    • 25
    • 25
    • 10
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human DTNBP1
    Isotype
    IgG
    Top Product
    Discover our top product DTNBP1 Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    DTNBP1 (Dystrobrevin Binding Protein 1 (DTNBP1))
    Autre désignation
    DTNBP1 (DTNBP1 Produits)
    Synonymes
    anticorps 5430437B18Rik, anticorps AW048963, anticorps Bloc1s8, anticorps dysbindin, anticorps sdy, anticorps BLOC1S8, anticorps DBND, anticorps HPS7, anticorps My031, anticorps SDY, anticorps dtnbp1, anticorps zgc:56462, anticorps MGC83903, anticorps dbnd, anticorps hps7, anticorps my031, anticorps MGC85477, anticorps DTNBP1, anticorps CG6856, anticorps Ddysb, anticorps Dmel\\CG6856, anticorps si:ch211-285p6.1, anticorps dystrobrevin binding protein 1, anticorps Dysbindin, anticorps dystrobrevin binding protein 1a, anticorps dystrobrevin binding protein 1 L homeolog, anticorps dystrobrevin binding protein 1 S homeolog, anticorps dystrobrevin binding protein 1b, anticorps Dtnbp1, anticorps DTNBP1, anticorps dtbp1, anticorps dtnbp1a, anticorps dtnbp1.L, anticorps dtnbp1.S, anticorps dtnbp1, anticorps Dysb, anticorps dtnbp1b
    Sujet

    Synonyms: SDY, DBND, HPS7, My031, BLOC1S8, Dysbindin, Biogenesis of lysosome-related organelles complex 1 subunit 8, BLOC-1 subunit 8, Dysbindin-1, Dystrobrevin-binding protein 1, Hermansky-Pudlak syndrome 7 protein, HPS7 protein, DTNBP1

    Background: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway.

    ID gène
    84062
    UniProt
    Q96EV8
    Pathways
    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling
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