APCDD1 anticorps

N° du produit ABIN731408

Détail du produit anti-APCDD1 anticorps

Antigène: APCDD1 (Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APCDD1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human APCDD1

Isotype: IgG

Information d'application

Indications d'application: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur APCDD1

Antigène: APCDD1 (Adenomatosis Polyposis Coli Down-Regulated 1 (APCDD1))

Autre désignation: Apcdd1 (APCDD1 Produits)

Synonymes: anticorps drapc1, anticorps xPgo, anticorps APCDD1, anticorps Pgo1, anticorps cAPCDD1, anticorps B7323, anticorps DRAPC1, anticorps HHS, anticorps HTS, anticorps AB023957, anticorps AU041258, anticorps Drapc1, anticorps EIG180, anticorps adenomatosis polyposis coli down-regulated 1, anticorps APC down-regulated 1, anticorps adenomatosis polyposis coli down-regulated 1 L homeolog, anticorps apcdd1, anticorps APCDD1, anticorps Apcdd1, anticorps apcdd1.L

Sujet:

Synonyms: adenomatosio polyposis coli down-regulated 1, Adenomatosis polyposis coli down regulated 1, Adenomatosis polyposis coli down regulated 1 protein, APCDD 1, B7323, DRAPC1, FP7019, Protein APCDD1, APCD1_HUMAN.

Background: APCDD1 is a novel protein that has been shown to be a target of Wnt/beta catenin signaling pathway in cancer cell lines. APCDD1 is overexpressed in colorectal carcinogenesis and is deregulated in CTNNB1 mutated Wilms tumors.[FUNCTION] Probably plays a role in colorectal tumorigenesis. May be a developmental target gene of the Wnt/Beta-catenin pathway.[SUBCELLULAR LOCATION] Membrane, Single-pass type I membrane protein (Potential). [TISSUE SPECIFICITY] Abundantly expressed in heart, pancreas, prostate and ovary. Moderately expressed in lung, liver, kidney, spleen, thymus, colon and peripheral lymphocytes. [INDUCTION] Transcriptionally regulated by the CTNNB1/TF7L2complex.

ID gène: 147495