VEGFC anticorps (AA 321-415)

N° du produit ABIN731723

Détail du produit anti-VEGFC anticorps

Antigène: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Épitope: AA 321-415

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VEGFC est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse VEGF-C

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-VEGFC (ABIN731723)

Alunno, Ibba-Manneschi, Bistoni, Rosa, Caterbi, Gerli, Manetti: "Mobilization of lymphatic endothelial precursor cells and lymphatic neovascularization in primary Sjögren's syndrome." dans: Journal of cellular and molecular medicine, Vol. 20, Issue 4, pp. 613-22, (2016) (PubMed).

He, Qi, Jia, Wang, Wang, Song, Fu, Li, Luo: "Tumor cell-secreted angiogenin induces angiogenic activity of endothelial cells by suppressing miR-542-3p." dans: Cancer letters, Vol. 368, Issue 1, pp. 115-25, (2015) (PubMed).

Zhuo, Jia, Song, Lu, Ding, Wang, Song, Fu, Luo: "The CXCL12-CXCR4 chemokine pathway: a novel axis regulates lymphangiogenesis." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 19, pp. 5387-98, (2012) (PubMed).

Détails sur VEGFC

Antigène: VEGFC (Vascular Endothelial Growth Factor C (VEGFC))

Autre désignation: VEGF-C (VEGFC Produits)

Synonymes: anticorps VEGFC, anticorps vegf-c, anticorps xvegf-c, anticorps Flt4-L, anticorps VRP, anticorps AW228853, anticorps VEGF-C, anticorps vascular endothelial growth factor c, anticorps vascular endothelial growth factor C, anticorps vascular endothelial growth factor C S homeolog, anticorps vegfc, anticorps VEGFC, anticorps vegfc.S, anticorps Vegfc

Sujet:

Synonyms: VEGF-C, AW228853, Vascular endothelial growth factor C, Flt4 ligand, Flt4-L, Vascular endothelial growth factor-related protein, VRP, Vegfc

Background: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.

ID gène: 22341

UniProt: P97953

Pathways: Signalisation RTK, Signaling Events mediated by VEGFR1 and VEGFR2