FDCSP anticorps (AA 18-85) (Biotin)

N° du produit ABIN734155

Détail du produit anti-FDCSP anticorps (Biotin)

Antigène: FDCSP (C4orf7) (Chromosome 4 Open Reading Frame 7 (C4orf7))

Épitope: AA 18-85

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FDCSP est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Homologie: Rat,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from rat FDC-SP

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FDCSP

Antigène: FDCSP (C4orf7) (Chromosome 4 Open Reading Frame 7 (C4orf7))

Autre désignation: FDC-SP (C4orf7 Produits)

Synonymes: anticorps FDC-SP, anticorps C4orf7, anticorps cDNA sequence BC037156, anticorps follicular dendritic cell secreted protein, anticorps BC037156, anticorps FDCSP

Sujet:

Synonyms: FDC, FDCs, Follicular dendritic cell, Follicular dendritic cell secreted protein, Follicular dendritic cell, Follicular dendritic cell secreted peptide, FDC secreted protein.

Background: Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles. This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell. It is purely a resident of the follicles of secondary lymphoid organs. B cells form germinal centers around follicular dendritic cells in lymphoid organs. Dendritic cells form from monocytes, white blood cells which circulate in the body and, depending on the right signal, can turn into dendritic cells or macrophages. The monocytes in turn are formed from stem cells in the bone marrow.In normal tissue this antibody identifies dendritic cells and a proportion of B lymphocytes. Evidence in pathological tissue and functional studies suggests it binds to an epitope expressed by antigen presenting cells. Within the macrophage/dendritic cell populations the epitope seen by RFD1 is coexpressed with RFD7 by a subset of cells that exhibit suppressive activity on T cell stimulation.

ID gène: 494224

UniProt: Q5R1M6