Haptoglobin anticorps (AA 251-350)

N° du produit ABIN734738

Détail du produit anti-Haptoglobin anticorps

Antigène: Haptoglobin (HP)

Épitope: AA 251-350

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Haptoglobin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificité: This protein may interact with Peptidase S1 Domain in LPA.

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Hpt

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Haptoglobin (ABIN734738)

Kälsch, Pott, Takeda, Kumamoto, Möllmann, Canbay, Sitek, Baba: "Bathing in carbon dioxide-enriched water alters protein expression in keratinocytes of skin tissue in rats." dans: International journal of biometeorology, (2016) (PubMed).

Détails sur Haptoglobin

Antigène: Haptoglobin (HP)

Abstract: HP Produits

Synonymes: anticorps HP, anticorps wu:fb64e01, anticorps BP, anticorps HP2ALPHA2, anticorps HPA1S, anticorps HP-1, anticorps HPR, anticorps Zonulin, anticorps haptoglobin, anticorps haptoglobin-like, anticorps HP, anticorps hp, anticorps Hp, anticorps LOC479668, anticorps LOC101102413

Sujet:

Synonyms: BP, HPA1S, HP2ALPHA2, Haptoglobin, Zonulin, HP

Background: As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an Antimicrobial, Antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway. Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.

ID gène: 3240

UniProt: P00738

Pathways: Transition Metal Ion Homeostasis