ITGA7 anticorps (AA 701-800)

N° du produit ABIN734858

Détail du produit anti-ITGA7 anticorps

Antigène: ITGA7 (Integrin, alpha 7 (ITGA7))

Épitope: AA 701-800

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGA7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Integrin alpha 7

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-ITGA7 (ABIN734858)

Tang, Li, Wang, Threadgill, Xiao, Mou, Song, Kuang, Yang, Yang, Gao, Wang, Meng: "ART1 promotes starvation-induced autophagy: a possible protective role in the development of colon carcinoma." dans: American journal of cancer research, Vol. 5, Issue 2, pp. 498-513, (2015) (PubMed).

Détails sur ITGA7

Antigène: ITGA7 (Integrin, alpha 7 (ITGA7))

Autre désignation: Integrin alpha 7/ITGA7 (ITGA7 Produits)

Synonymes: anticorps [a]7, anticorps alpha7, anticorps integrin alpha 7, anticorps integrin subunit alpha 7, anticorps Itga7, anticorps ITGA7

Sujet:

Synonyms: Integrin alpha-7, ITGA7, UNQ46/PRO768

Background: Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.

ID gène: 3679

UniProt: Q13683

Pathways: Integrin Complex