Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

HDAC3 anticorps

HDAC3 Reactivité: Humain, Souris, Rat, Chien, Poulet WB, IHC (p), IF (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN734903
  • Antigène Voir toutes HDAC3 Anticorps
    HDAC3 (Histone Deacetylase 3 (HDAC3))
    Reactivité
    • 105
    • 64
    • 61
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Poulet
    Hôte
    • 79
    • 25
    • 1
    Lapin
    Clonalité
    • 81
    • 24
    Polyclonal
    Conjugué
    • 61
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HDAC3 est non-conjugé
    Application
    • 90
    • 46
    • 33
    • 27
    • 26
    • 26
    • 16
    • 15
    • 13
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Humain, Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human HDAC3
    Isotype
    IgG
    Top Product
    Discover our top product HDAC3 Anticorps primaire
  • Indications d'application
    WB(1:100-500)
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    HDAC3 (Histone Deacetylase 3 (HDAC3))
    Autre désignation
    HDAC3/HD3 (HDAC3 Produits)
    Sujet

    Synonyms: HD3, RPD3, RPD3-2, Histone deacetylase 3, SMAP45, HDAC3

    Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Participates in the BCL6 transcriptional repressor activity by deacetylating the H3 'Lys-27' (H3K27) on enhancer elements, antagonizing EP3 acetyltransferase activity and repressing proximal gene expression. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1, increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation.

    Poids moléculaire
    47kDa
    ID gène
    8841
    UniProt
    O15379
    Pathways
    Neurotrophin Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Vous êtes ici:
Support technique