Integrin Alpha3, Beta1 (AA 976-1025) anticorps

N° du produit ABIN737031

Détail du produit

Antigène: Integrin Alpha3, Beta1

Épitope: AA 976-1025

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: Mixed KLH conjugated synthetic peptide derived from human Integrin Alpha 3(976-1025/1051) + Beta 1(35-47/798)

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Référence

Wang, Zhang, Song, Wang, Guo, Zhang, Li, Han, Miao, Li: "PAK1 regulates RUFY3-mediated gastric cancer cell migration and invasion." dans: Cell death & disease, Vol. 6, pp. e1682, (2015) (PubMed).

Détail du antigène

Antigène: Integrin Alpha3, Beta1

Autre désignation: Integrin Alpha 3 + Beta 1

Sujet:

Synonyms: Integrin Alpha 3 / Beta 1, Integrin VLA 4 beta subunit, Alpha 3 subunit of VLA 3 receptor, CD29, CD49C, Fibronectin receptor, Fibronectin receptor beta subunit, Galactoprotein B3, GAPB3, VL3A, VLA 3 alpha chain, VLA3a.

Background: alpha3beta1 integrin is a laminin receptor with apparently diverse functions. In epithelial cells it acts as a receptor for the basement membrane, whereas in neuronal and possibly tumor cells it mediates migration. Interactions of alpha3beta1 integrin with tetraspanin proteins may provide clues to how it transduces signals that affect cell behavior.

ID gène: 3675, 3688

UniProt: P26006, P05556