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KLF2/4 anticorps (AA 415-513) (Biotin)

KLF2/4 Reactivité: Humain, Souris, Rat WB, IHC (fro), IHC (p), ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN737123
  • Antigène Tous les produits KLF2/4
    KLF2/4 (Kruppel-Like Factor 2/4 (KLF2/4))
    Épitope
    AA 415-513
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 15
    Lapin
    Clonalité
    • 15
    Polyclonal
    Conjugué
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KLF2/4 est conjugé à/à la Biotin
    Application
    • 15
    • 14
    • 13
    • 13
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
    Specificité
    This antibody may crossreact with KLF2 due to high sequence similarity.
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Cow,Sheep,Pig,Horse,Chicken,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human KLF4
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    KLF2/4 (Kruppel-Like Factor 2/4 (KLF2/4))
    Abstract
    KLF2/4 Produits
    Sujet

    Synonyms: EZF, GKLF, Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4

    Background: Transcription factor, can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

    ID gène
    9314
    UniProt
    O43474
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