SPARC anticorps (AA 101-200)

N° du produit ABIN738141

Détail du produit anti-SPARC anticorps

Antigène: SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))

Épitope: AA 101-200

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPARC est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SPARC

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-SPARC (ABIN738141)

Zong, Zeng, Zou, Li, Fang, Lu, Xiao, Zhang: "Effects of Polygonatum sibiricum polysaccharide on the osteogenic differentiation of bone mesenchymal stem cells in mice." dans: International journal of clinical and experimental pathology, Vol. 8, Issue 6, pp. 6169-80, (2015) (PubMed).

Kurtul, Eroglu, Unal, Tasdemir, Orhan, Zararsiz, Baran, Kaplan, Kontas: "Prognostic Value of SPARC Expression in Unresectable NSCLC Treated with Concurrent Chemoradiotherapy." dans: Asian Pacific journal of cancer prevention : APJCP, Vol. 15, Issue 20, pp. 8911-6, (2014) (PubMed).

Chen, Wang, Xi, Xue, He, Zhang, Zhao: "SPARC is a key regulator of proliferation, apoptosis and invasion in human ovarian cancer." dans: PLoS ONE, Vol. 7, Issue 8, pp. e42413, (2012) (PubMed).

Détails sur SPARC

Antigène: SPARC (Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) (SPARC))

Autre désignation: SPARC (SPARC Produits)

Synonymes: anticorps ON, anticorps AA517111, anticorps BM-40, anticorps hm:zeh0062, anticorps SPARC, anticorps sparc, anticorps secreted protein acidic and cysteine rich, anticorps secreted acidic cysteine rich glycoprotein, anticorps secreted protein, acidic, cysteine-rich (osteonectin), anticorps secreted protein, acidic, cysteine-rich (osteonectin) L homeolog, anticorps secreted protein, acidic, cysteine-rich (osteonectin) S homeolog, anticorps SPARC, anticorps Sparc, anticorps sparc, anticorps sparc.L, anticorps sparc.S

Sujet:

Synonyms: ON, SPARC, Basement-membrane protein 4, BM-4, Osteonectin, Secreted protein acidic and rich in cysteine

Background: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites, an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.

ID gène: 6678

UniProt: P09486

Pathways: Autophagy