ASCL1 anticorps (AA 151-236)

N° du produit ABIN738471

Détail du produit anti-ASCL1 anticorps

Antigène: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Épitope: AA 151-236

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASCL1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow,Sheep

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ASCL1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-ASCL1 (ABIN738471)

Misra, Luo, Li, Matise, Xiang: "Asymmetric activation of Dll4-Notch signaling by Foxn4 and proneural factors activates BMP/TGFβ signaling to specify V2b interneurons in the spinal cord." dans: Development (Cambridge, England), Vol. 141, Issue 1, pp. 187-98, (2014) (PubMed).

Détails sur ASCL1

Antigène: ASCL1 (Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1))

Autre désignation: ASCL1 (ASCL1 Produits)

Synonymes: anticorps ASH1, anticorps HASH1, anticorps MASH1, anticorps bHLHa46, anticorps AI225900, anticorps Mash1, anticorps ASCL1, anticorps Zash-1a, anticorps ash, anticorps asha, anticorps id:ibd5085, anticorps im:7138587, anticorps si:dkey-264k15.2, anticorps zash1a, anticorps zasha, anticorps Xash1, anticorps ascl1-A, anticorps Zash-1b, anticorps ashb, anticorps zashb, anticorps achaete-scute family bHLH transcription factor 1, anticorps achaete-scute family bHLH transcription factor 1a, anticorps achaete-scute family bHLH transcription factor 1 L homeolog, anticorps achaete-scute complex homolog 1, anticorps achaete-scute family bHLH transcription factor 1b, anticorps ASCL1, anticorps Ascl1, anticorps ascl1a, anticorps ascl1.L, anticorps LOC100220505, anticorps ascl1b

Sujet:

Synonyms: ASH1, HASH1, MASH1, bHLHa46, Achaete-scute homolog 1, ASH-1, Class A basic helix-loop-helix protein 46, ASCL1

Background: Transcription factor that controls transcriptional expression of its target genes by binding to the E box (5'-CANNTG-3'). Plays a role at early stages of development of specific neural lineages in most regions of the CNS, and of several lineages in the PNS. Acts synergistically with FOXN4 to specify the identity of V2b neurons rather than V2a from bipotential p2 progenitors during spinal cord neurogenesis, probably through DLL4-NOTCH signaling activation. Essential for the generation of olfactory and autonomic neurons (By similarity).

ID gène: 429

UniProt: P50553

Pathways: Dopaminergic Neurogenesis