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CD47 anticorps (AA 241-323)

Name: CD47 anticorps (AA 241-323)
SKU: ABIN739530
Price: 384.62 EUR
Availability: InStock

CD47 Reactivité: Souris, Rat FACS, WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat tongue tissue labeled with Anti-CD47 MER6 Polyclonal Antibody, unconjugated (ABIN739530) at 1: 200 followed by incubation with conjugated secondary antibody (CD47 anticorps (AA 241-323))

IHC

Formalin-fixed and paraffin embedded rat tongue tissue labeled with Anti-CD47/MER6 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody (CD47 anticorps (AA 241-323))

IHC (p)

RSC96 cells probed with CD47/MER6 Polyclonal Antibody, Unconjugated at 1:100 for 30 minutes followed by incubation with a PE conjugated secondary (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange). (CD47 anticorps (AA 241-323))

FACS

IHC

4 images

(1 reference)

N° du produit ABIN739530

Fiche de données

Antigène Voir toutes CD47 Anticorps

CD47
Épitope
15

15

8

8

7

5

4

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 241-323
Reactivité
122

51

26

6

3

2

2

2

1

1

1

1
Souris, Rat
Hôte
77

65

9

1
Lapin
Anticorps secondaires appropriés
Clonalité
78

72

1
Polyclonal
Conjugué
66

13

12

7

5

5

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
Cet anticorp CD47 est non-conjugé
Application
87

84

42

39

35

25

25

18

16

15

13

10

7

5

4

3

3

3

2

2

2

2

2

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée

Souris, Rat

Homologie

Human,Rabbit

Purification

Purified by Protein A.

Immunogène

KLH conjugated synthetic peptide derived from human CD47/MER6

Isotype

IgG

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CD47 Reactivité: Humain, Souris, Rat WB, IF, IHC, ELISA, ICC Hôte: Lapin Polyclonal unconjugated

Indications d'application

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur

ProClin

Précaution d'utilisation

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption

12 months
Miedel, Dishowitz, Myers, Dopkin, Yu, Miclau, Marcucio, Ahn, Hankenson: "Disruption of thrombospondin-2 accelerates ischemic fracture healing." dans: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 31, Issue 6, pp. 935-43, (2013) (PubMed).
Antigène

CD47

Autre désignation

CD47/MER6 (CD47 Produits)

Synonymes

anticorps IAP, anticorps MER6, anticorps OA3, anticorps 9130415E20Rik, anticorps AA407862, anticorps AI848868, anticorps AW108519, anticorps B430305P08Rik, anticorps Itgp, anticorps CD47/IAP, anticorps alkaline phosphatase, intestinal, anticorps CD47 molecule, anticorps CD47 antigen (Rh-related antigen, integrin-associated signal transducer), anticorps Cd47 molecule, anticorps ALPI, anticorps CD47, anticorps Cd47

Sujet

Synonyms: IAP, OA3, MER6, Leukocyte surface antigen CD47, Antigenic surface determinant protein OA3, Integrin-associated protein, Protein MER6, CD47
Background: Has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. Plays an important role in memory formation and synaptic plasticity in the hippocampus (By similarity). Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection.

ID gène

961

UniProt

Q08722