CCL4 anticorps (AA 26-92)

N° du produit ABIN740805

Détail du produit anti-CCL4 anticorps

Antigène: CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

Épitope: AA 26-92

Reactivité: Humain, Souris, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Lapin

Homologie: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse CCL4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-CCL4 (ABIN740805)

Lee, Perry, Heywood, Reese, Bonner, Hatfield, Silver, Visconti, Hoffman, Tourkina: "Caveolin-1 regulates chemokine receptor 5-mediated contribution of bone marrow-derived cells to dermal fibrosis." dans: Frontiers in pharmacology, Vol. 5, pp. 140, (2014) (PubMed).

Détails sur CCL4

Antigène: CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))

Autre désignation: CCL4 (CCL4 Produits)

Synonymes: anticorps ACT2, anticorps AT744.1, anticorps G-26, anticorps HC21, anticorps LAG-1, anticorps LAG1, anticorps MIP-1-beta, anticorps MIP1B, anticorps MIP1B1, anticorps SCYA2, anticorps SCYA4, anticorps CCL4, anticorps K203, anticorps Mip1-b, anticorps Scya4, anticorps MIP-1beta, anticorps MIP-1BETA, anticorps MIP1b, anticorps SCY4A, anticorps Act-2, anticorps MIP-1B, anticorps Mip1b, anticorps ACT-2, anticorps AT744.2, anticorps CCL4L, anticorps SCYA4L, anticorps SCYA4L1, anticorps SCYA4L2, anticorps C-C motif chemokine ligand 4, anticorps chemokine (C-C motif) ligand 4, anticorps chemokine (C-C motif) ligand 4-like 1, anticorps C-C motif chemokine ligand 4 like 1, anticorps CCL4, anticorps Ccl4, anticorps CCL4L1

Sujet:

Synonyms: MIP-1 Beta, Macrophage Inflammatory Protein 1 beta, MIP-1 Beta, MIP-1_, Secreted protein G 26, ACT 2, ACT2, AT744.1, CC chemokine ligand 4, CCL4, ccl4l 1, CCL4L1, Chemokine CC Mot Ligand 4, G 26 T lymphocyte secreted protein, HC21, LAG 1, LAG1, Lymphocyte activation gene 1, Lymphocyte activation gene 1 protein, Macrophage inflammatory protein 1 beta, MGC104418, MGC126025, MGC126026, MIP1 beta, MIP1B, MIP1B1, PAT 744, Protein H400, SCYA2, SCYA4, Secreted protein G26, SIS gamma, Small inducible cytokine A4, T cell activation protein 2, CCL4_MOUSE,

Background: MIP1 alpha and MIP1 beta were originally co-purified from medium conditioned by an LPS-stimulated murine macrophage cell line. Human MIP1 beta refers to the products of several independently cloned cDNAs, including Act2, PAT 744, hH400, G26, HIMAP, HC21, and MAD 5a. The predicted protein products of these cDNAs represent variants that are between 94 % - 98 % identical and these proteins are all approximately 75 % homologous to murine MIP1 beta. MIP1 beta also shares approximately 70 % amino acid identity with MIP1 alpha. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. The MIP1 proteins have chemoattractant and adhesive effects on lymphocytes, with MIP1 alpha and MIP1 beta preferentially attracting CD8+ and CD4+ T cells, respectively. A signal transducing receptor designated the CC chemokine receptor 1 (CC CKR1) with seven transmembrane domains that binds MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities has been isolated.

ID gène: 6351