TRIM63 anticorps (AA 251-353)

N° du produit ABIN741750

Détail du produit anti-TRIM63 anticorps

Antigène: TRIM63 (Tripartite Motif Containing 63 (TRIM63))

Épitope: AA 251-353

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM63 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MuRF1/Trim63

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-TRIM63 (ABIN741750)

Lu, Wang, Xie, Zhang, Sun: "Tumor necrosis factor-like weak inducer of apoptosis regulates quadriceps muscle atrophy and fiber-type alteration in a rat model of chronic obstructive pulmonary disease." dans: Tobacco induced diseases, Vol. 15, pp. 43, (2017) (PubMed).

Lin, Hanson, Betik, Brennan-Speranza, Hayes, Levinger: "Hindlimb Immobilization, But Not Castration, Induces Reduction of Undercarboxylated Osteocalcin Associated With Muscle Atrophy in Rats." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 11, pp. 1967-1978, (2016) (PubMed).

Détails sur TRIM63

Antigène: TRIM63 (Tripartite Motif Containing 63 (TRIM63))

Autre désignation: MuRF1/Trim63 (TRIM63 Produits)

Synonymes: anticorps IRF, anticorps MURF1, anticorps MURF2, anticorps RNF28, anticorps SMRZ, anticorps Murf, anticorps Murf1, anticorps Rnf28, anticorps MuRF1, anticorps RF1, anticorps rnf30, anticorps MGC80210, anticorps TRIM63, anticorps MuRF, anticorps fc50c07, anticorps trim63, anticorps wu:fc50c07, anticorps zgc:86757, anticorps tripartite motif containing 63, anticorps tripartite motif-containing 63, anticorps tripartite motif containing 63 S homeolog, anticorps tripartite motif containing 63a, anticorps TRIM63, anticorps Trim63, anticorps trim63.S, anticorps trim63a

Sujet:

Synonyms: MuRF 1, MuRF-1, Muscle-specic RING finger protein 1, Muscle-specic RING finger protein 1, E3 ubiquitin-protein ligase TRIM63, FLJ32380, IRF, MURF1, MURF 1, MURF2, RNF28, SMRZ, Iris ring finger protein, Muscle specic ring finger protein 2, Ring finger protein 28, RNF28, SMRZ, Striated muscle RING zinc finger protein, TRIM 63, TRIM63, Tripartite mot containing 63, Tripartite mot containing protein 63, Ubiquitin ligase TRIM63.

Background: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq].

ID gène: 84676