MAP2K7 anticorps (pSer271, pThr275)

N° du produit ABIN743918

Détail du produit anti-MAP2K7 anticorps

Antigène: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Épitope: pSer271, pThr275

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP2K7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human MKK7 around the phosphorylation site of Ser271/Thr275

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MAP2K7

Antigène: MAP2K7 (Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))

Autre désignation: MKK7 + (MAP2K7 Produits)

Synonymes: anticorps MAP2K7, anticorps 2, anticorps JNKK, anticorps Jnkk2, anticorps Mapkk7, anticorps Mek7, anticorps Mkk7, anticorps MAPKK7, anticorps MKK7, anticorps PRKMK7, anticorps SAPKK-4, anticorps SAPKK4, anticorps 5930412N11Rik, anticorps JNKK 2, anticorps MAPKK 7, anticorps MEK 7, anticorps Prkmk7, anticorps sek2, anticorps si:ch211-254d18.2, anticorps map2k7-A, anticorps mitogen-activated protein kinase kinase 7, anticorps mitogen activated protein kinase kinase 7, anticorps mitogen-activated protein kinase kinase 7 L homeolog, anticorps MAP2K7, anticorps Map2k7, anticorps map2k7, anticorps map2k7.L

Sujet:

Synonyms: MEK7 phospho S277 + T275, MEK7 phospho Ser277 + Thr275, p-MEK7 S277 + T275, p-MEK7 Ser277 + Thr275, c-Jun N-terminal kinase kinase 2, Dual specicity mitogen activated protein kinase kinase 7, Dual specicity mitogen-activated protein kinase kinase 7, JNK activating kinase 2, JNK kinase 2, JNK-activating kinase 2, Jnkk 2, Jnkk-2, Jnkk2, MAP kinase kinase 7, MAP2K7, MAPK/ERK kinase 7, MAPKK 7, MAPKK-7, MAPKK7, MEK 7, Mitogen Activated Protein Kinase kinase 7, MKK 7, MKK-7, MKK7, MP2K7_HUMAN, PRKMK 7, PRKMK-7, PRKMK7, Sek 2, Sek-2, Sek2.

Background: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq, Jul 2008].

ID gène: 5609

Pathways: Signalisation MAPK, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling