PEA15 anticorps (pSer116)

N° du produit ABIN744698

Détail du produit anti-PEA15 anticorps

Antigène: PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))

Épitope: pSer116

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PEA15 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human PEA15 around the phosphorylation site of Ser116

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-PEA15 (ABIN744698)

Kim, Kang: "PKC, AKT and ERK1/2-Mediated Modulations of PARP1, NF-κB and PEA15 Activities Distinctly Regulate Regional Specific Astroglial Responses Following Status Epilepticus." dans: Frontiers in molecular neuroscience, Vol. 12, pp. 180, (2019) (PubMed).

Détails sur PEA15

Antigène: PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))

Autre désignation: PEA15 (PEA15 Produits)

Synonymes: anticorps HMAT1, anticorps HUMMAT1H, anticorps MAT1, anticorps MAT1H, anticorps PEA-15, anticorps PED, anticorps Pea15a, anticorps PEA15, anticorps DKFZp459O1410, anticorps proliferation and apoptosis adaptor protein 15, anticorps phosphoprotein enriched in astrocytes 15, anticorps proliferation and apoptosis adaptor protein 15 L homeolog, anticorps Astrocytic phosphoprotein PEA-15, anticorps PEA15, anticorps Pea15, anticorps pea15.L, anticorps pea15

Sujet:

Synonyms: Astrocytic phosphoprotein PEA 15, Astrocytic phosphoprotein PEA15, HMAT 1, HMAT1, Homolog of mouse MAT 1 oncogene, Homolog of mouse MAT1 oncogene, HUMMAT 1H, HUMMAT1H, MAT 1, MAT 1H, MAT1, MAT1H, PEA 15, PEA-15_ PEA15 protein, PED, Phosphoprotein enriched in astrocytes 15, Phosphoprotein enriched in astrocytes 15kD, Phosphoprotein enriched in diabetes, PEA15_HUMAN.

Background: PED/PEA 15 (Phosphoprotein Enriched in Diabetes/Phosphoprotein Enriched in Astrocytes 15 kDa) is a widely expressed 15 kDa protein comprised of an N terminal region containing a canonical Death Effector Domain (DED) sequence and a nuclear export signal, and a C terminal region containing two serine phosphorylation sites. PED/PEA 15 has been implicated in the regulation of multiple cellular processes including apoptosis, integrin activation, and insulin sensitive glucose transport in insulin responsive cells. Phosphorylation of both serine 104 (a Protein Kinase C site) and serine 116 (a substrate of CaMKII and Akt) is required for PED/PEA 15 function.

ID gène: 8682