RCC1 anticorps (pSer11) (Biotin)

N° du produit ABIN745165

Détail du produit anti-RCC1 anticorps (Biotin)

Antigène: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Épitope: pSer11

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RCC1 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human RCC1 around the phosphorylation site of Ser11

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur RCC1

Antigène: RCC1 (Regulator of Chromosome Condensation 1 (RCC1))

Autre désignation: RCC1 (RCC1 Produits)

Synonymes: anticorps Chc1, anticorps zgc:65796, anticorps zgc:77114, anticorps wu:fj77f08, anticorps rcc1, anticorps chc1-a, anticorps BJ1, anticorps CG10480, anticorps CG18640 (Bj1), anticorps Dmel\\CG10480, anticorps RCC1, anticorps RanGEF, anticorps Rcc1, anticorps dRCC1, anticorps inxs, anticorps sdt, anticorps xrcc1, anticorps chc1-b, anticorps MGC115703, anticorps MGC132085, anticorps CHC1, anticorps RCC1-I, anticorps SNHG3-RCC1, anticorps 4931417M11Rik, anticorps AI326872, anticorps regulator of chromosome condensation 1, anticorps regulator of chromosome condensation 1 L homeolog, anticorps Regulator of chromosome condensation 1, anticorps N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted, anticorps regulator of chromosome condensation 1 S homeolog, anticorps rcc1, anticorps RCC1, anticorps rcc1.L, anticorps Rcc1, anticorps rcc1.S

Sujet:

Synonyms: Cell cycle regulatory protein, CHC 1, CHC1, Chromosome condensation 1, Chromosome condensation protein 1, Guanine nucleotide releasing protein, HERC2, Ran GEF, RanGEF, RCC 1, RCC1 I, Regulator of chromosome condensation 1, Regulator of chromosome condensation, SHEP1, RCC1_HUMAN.

Background: Ran GTPase plays important roles in nucleocytoplasmic transport in interphase and in both spindle formation and nuclear envelope (NE) assembly during mitosis. The latter functions rely on the presence of high local concentrations of GTP bound Ran near mitotic chromatin. RanGTP localization has been proposed to result from the association of Ran's GDP/GTP exchange factor, RCC1, with chromatin , but Ran is shown here to bind directly to chromatin in two modes, either dependent or independent of RCC1, and, where bound, to increase the affinity of chromatin for NE membranes.

ID gène: 1104

Pathways: Chromatin Binding, Protein targeting to Nucleus