ARAF anticorps (pSer299)

N° du produit ABIN745328

Détail du produit anti-ARAF anticorps

Antigène: ARAF (V-Raf Murine Sarcoma 3611 Viral Oncogene Homolog (ARAF))

Épitope: pSer299

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARAF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human A Raf around the phosphorylation site of Ser299

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ARAF

Antigène: ARAF (V-Raf Murine Sarcoma 3611 Viral Oncogene Homolog (ARAF))

Autre désignation: A Raf (ARAF Produits)

Synonymes: anticorps zgc:92074, anticorps wu:fk45h07, anticorps ARAF, anticorps a-raf, anticorps araf, anticorps araf1, anticorps pks2, anticorps rafa1, anticorps A-RAF, anticorps ARAF1, anticorps PKS2, anticorps RAFA1, anticorps 1200013E08Rik, anticorps A-Raf, anticorps AW495444, anticorps Araf1, anticorps A-Raf proto-oncogene, serine/threonine kinase, anticorps A-Raf proto-oncogene, serine/threonine kinase L homeolog, anticorps A-Raf proto-oncogene, serine/threonine kinase S homeolog, anticorps Araf proto-oncogene, serine/threonine kinase, anticorps araf, anticorps ARAF, anticorps araf.L, anticorps araf.S, anticorps Araf

Sujet:

Synonyms: A RAF phospho S299, p-A RAF phospho S299,A raf 1, A Raf proto oncogene serine/threonine protein kinase, ARAF 1, ARAF, ARaf proto oncogene serine/threonine protein kinase, ARAF1, Oncogene Araf1, Oncogene PKS2, PKS 2, PKS, PKS2, Proto oncogene Pks, RAFA 1, RAFA1, Ras binding protein DA Raf, v raf murine sarcoma 3611 viral oncogene homolog, v raf murine sarcoma 3611 viral oncogene homolog 1, v raf oncogene homolog 1 murine sarcoma 3611 virus, ARAF_HUMAN.

Background: The RAF family of signaling proteins has three isoforms: A RAF, RAF 1 and B RAF. These proteins are instrumental in forwarding the stimulus generated by mitogens from monomeric G proteins to the MAP kinase pathway. RAF 1 is known to be downstream of Ras and binds to it by an N terminal noncatalytic domain. This domain is conserved in A RAF and B RAF. 14-3-3 is also known to be an activator of RAFs. Activated RAF directly phosphorylates and activates MEK. A RAF is expressed at a very high concentration in urogenital and kidney tissues.

ID gène: 369

UniProt: P10398

Pathways: Signalisation MAPK, Signalisation RTK, Hepatitis C