INPPL1 anticorps (pTyr986, pTyr987)

N° du produit ABIN745823

Détail du produit anti-INPPL1 anticorps

Antigène: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Épitope: pTyr986, pTyr987

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INPPL1 est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human SHIP2 around the phosphorylation site of Tyr986/987

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur INPPL1

Antigène: INPPL1 (Inositol Polyphosphate Phosphatase-Like 1 (INPPL1))

Autre désignation: INPPL1 + (INPPL1 Produits)

Synonymes: anticorps OPSMD, anticorps SHIP2, anticorps 51C, anticorps Ship2, anticorps inppl1, anticorps si:bz46j2.7, anticorps si:rp71-46j2.7, anticorps INPPL1, anticorps fc58a04, anticorps wu:fc58a04, anticorps zgc:198309, anticorps inositol polyphosphate phosphatase like 1, anticorps inositol polyphosphate phosphatase-like 1, anticorps inositol polyphosphate phosphatase-like 1b, anticorps phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2B, anticorps inositol polyphosphate phosphatase-like 1a, anticorps INPPL1, anticorps Inppl1, anticorps inppl1b, anticorps LOC100180571, anticorps inppl1a

Sujet:

Synonyms: 4, 5-trisphosphate 5-phosphatase 2, 51C protein, EC 3.1.3.n1, inositol polyphosphate phosphatase like 1, Inositol polyphosphate phosphatase like protein 1, Inositol polyphosphate phosphatase-like protein 1, INPPL-1, INPPL1, Phosphatidylinositol 3, Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2, Protein 51C, SH2 domain containing inositol 5' phosphatase 2, SH2 domain-containing inositol 5''-phosphatase 2, SH2 domain-containing inositol phosphatase 2, SHIP-2, SHIP2, SHIP2_HUMAN.

Background: The steady state of protein tyrosyl phosphorylation in cells is regulated by the opposing action of tyrosine kinases and protein tyrosine phosphatases (PTPs). Several groups have independently identified a non transmembrane PTP, designated SHPTP1 (also known as PTP1C, HCP and SHP), which is primarily expressed in hematopoietic cells and characterized by the presence of two SH2 domains N terminal to the PTP domain. A second and much more widely expressed PTP with SH2 domains, SHPTP2 (also designated PTP1D and Syp), has been identified. SHP2 is a protein tyrosine phosphatase that is widely expressed and plays a regulatory role in various cell signaling events that are important for many cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration.

ID gène: 3636

Pathways: Platelet-derived growth Factor Receptor Signaling