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tau anticorps (pSer396)

Name: tau anticorps (pSer396)
SKU: ABIN746453
Price: 384.62 EUR
Availability: InStock

Reactivité: Humain, Souris, Rat WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat brain labeled with Anti-phospho-Tau protein(Ser396) Polyclonal Antibody, Unconjugated (ABIN746453) at 1:200 followed by conjugation to the secondary antibody (tau anticorps (pSer396))

IHC

Formalin-fixed and paraffin embedded mouse brain labeled with Anti-phospho-Tau protein(Ser396) Polyclonal Antibody, Unconjugated (ABIN746453) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C and DAPI staining (tau anticorps (pSer396))

Formalin-fixed and paraffin embedded Human endometrium labeled with Anti-phospho-Tau protein(Ser396) Polyclonal Antibody, Unconjugated (ABIN746453) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C and DAPI staining (tau anticorps (pSer396))

3 images

(1 reference)

N° du produit ABIN746453

Fiche de données

Antigène Voir toutes tau Anticorps

tau (tau Protein)
Épitope
31

30

30

30

27

27

25

25

24

24

24

23

23

22

17

17

17

16

16

16

16

16

15

15

13

12

11

10

9

8

7

7

6

5

5

4

4

3

3

2

2

2

2

2

2

2

2

2

2

2
pSer396
Reactivité
579

541

538

42

28

27

18

7

3

2

2

1

1
Humain, Souris, Rat
Hôte
684

38

3

2
Lapin
Anticorps secondaires appropriés
Clonalité
661

65

1
Polyclonal
Conjugué
238

40

31

29

24

24

24

24

24

24

24

24

24

22

22

15

15

15

15

15

15

12

5

4

4

4

4

4

1

1
Cet anticorp tau est non-conjugé
Application
570

271

262

213

92

85

68

58

54

37

34

17

12

12

12

9

2

2

1

1
Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée

Humain, Souris, Rat

Homologie

Dog

Purification

Purified by Protein A.

Immunogène

KLH conjugated synthetic phosphopeptide derived from human Tau protein around the phosphorylation site of Ser396 [KT(p-S)T]

Isotype

IgG

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Indications d'application

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur

ProClin

Précaution d'utilisation

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption

12 months
Cai, Yan, Wang: "Minocycline alleviates beta-amyloid protein and tau pathology via restraining neuroinflammation induced by diabetic metabolic disorder." dans: Clinical interventions in aging, Vol. 8, pp. 1089-95, (2013) (PubMed).
Antigène

tau (tau Protein)

Abstract

tau Produits

Synonymes

anticorps DDPAC, anticorps FTDP-17, anticorps MAPTL, anticorps MSTD, anticorps MTBT1, anticorps MTBT2, anticorps PPND, anticorps TAU, anticorps tau, anticorps PHF-tau, anticorps microtubule associated protein tau, anticorps MAPT

Sujet

Synonyms: TAU, MSTD, PPND, DDPAC, MAPTL, MTBT1, MTBT2, FTDP-17, PPP1R13, Microtubule-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT
Background: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

ID gène

4137

UniProt

P10636