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ENOS anticorps (pSer1177)

NOS3 Reactivité: Humain, Rat, Souris WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN746468
  • Antigène Voir toutes ENOS (NOS3) Anticorps
    ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))
    Épitope
    • 33
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    • 17
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    • 1
    • 1
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    pSer1177
    Reactivité
    • 273
    • 152
    • 150
    • 13
    • 10
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Rat, Souris
    Hôte
    • 277
    • 30
    • 1
    Lapin
    Clonalité
    • 279
    • 29
    Polyclonal
    Conjugué
    • 118
    • 25
    • 17
    • 14
    • 10
    • 8
    • 8
    • 8
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    Cet anticorp ENOS est non-conjugé
    Application
    • 253
    • 103
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    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Sheep,Pig,Rabbit,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic phosphopeptide derived from human eNOS around the phosphorylation site of Ser1177
    Isotype
    IgG
    Top Product
    Discover our top product NOS3 Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Chen, Tan, Wu, Chai, Yeh, Chou, Chen, Dai: "Statins ameliorate pulmonary hypertension secondary to left ventricular dysfunction through the Rho-kinase pathway and NADPH oxidase." dans: Pediatric pulmonology, Vol. 52, Issue 4, pp. 443-457, (2016) (PubMed).

    Yin, Wan, Li, Jia, Sun, Pan, Wan: "Protective effect of Xin Mai Jia ultrafiltration extract on human umbilical vein endothelial cell injury induced by hydrogen peroxide and the effect on the NO-cGMP signaling pathway." dans: Experimental and therapeutic medicine, Vol. 8, Issue 1, pp. 38-48, (2014) (PubMed).

    Ikemura, Yamamoto, Motomura, Yamaguchi, Zhao, Iwasaki, Iwamoto: "Preventive effects of the anti-vasospasm agent via the regulation of the Rho-kinase pathway on the development of steroid-induced osteonecrosis in rabbits." dans: Bone, Vol. 53, Issue 2, pp. 329-35, (2013) (PubMed).

    Chuang, Lin, Huang, Chang, Liou, Chen, Chang, Chan et al.: "Peroxisome proliferator-activated receptors ?/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status ..." dans: Journal of neuroinflammation, Vol. 9, pp. 184, (2012) (PubMed).

  • Antigène
    ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))
    Autre désignation
    eNOS (NOS3 Produits)
    Synonymes
    anticorps ECNOS, anticorps eNOS, anticorps 2310065A03Rik, anticorps Nos-3, anticorps ecNOS, anticorps EC-NOS, anticorps NOSIII, anticorps cNOS, anticorps NOS, anticorps NOS3, anticorps eNos, anticorps ENOS, anticorps nitric oxide synthase 3, anticorps nitric oxide synthase 3, endothelial cell, anticorps NOS3, anticorps Nos3, anticorps nos3
    Sujet

    Synonyms: eNOS, ECNOS, Nitric oxide synthase, endothelial, Constitutive NOS, cNOS, EC-NOS, Endothelial NOS, NOS type III, NOSIII, NOS3

    Background: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.

    ID gène
    4846
    UniProt
    P29474
    Pathways
    ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
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