ENOS anticorps (pSer1177)

N° du produit ABIN746468

Détail du produit anti-ENOS anticorps

Antigène: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Épitope: pSer1177

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ENOS est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human eNOS around the phosphorylation site of Ser1177

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-ENOS (ABIN746468)

Chen, Tan, Wu, Chai, Yeh, Chou, Chen, Dai: "Statins ameliorate pulmonary hypertension secondary to left ventricular dysfunction through the Rho-kinase pathway and NADPH oxidase." dans: Pediatric pulmonology, Vol. 52, Issue 4, pp. 443-457, (2016) (PubMed).

Yin, Wan, Li, Jia, Sun, Pan, Wan: "Protective effect of Xin Mai Jia ultrafiltration extract on human umbilical vein endothelial cell injury induced by hydrogen peroxide and the effect on the NO-cGMP signaling pathway." dans: Experimental and therapeutic medicine, Vol. 8, Issue 1, pp. 38-48, (2014) (PubMed).

Ikemura, Yamamoto, Motomura, Yamaguchi, Zhao, Iwasaki, Iwamoto: "Preventive effects of the anti-vasospasm agent via the regulation of the Rho-kinase pathway on the development of steroid-induced osteonecrosis in rabbits." dans: Bone, Vol. 53, Issue 2, pp. 329-35, (2013) (PubMed).

Chuang, Lin, Huang, Chang, Liou, Chen, Chang, Chan et al.: "Peroxisome proliferator-activated receptors ?/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status ..." dans: Journal of neuroinflammation, Vol. 9, pp. 184, (2012) (PubMed).

Détails sur ENOS

Antigène: ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))

Autre désignation: eNOS (NOS3 Produits)

Synonymes: anticorps ECNOS, anticorps eNOS, anticorps 2310065A03Rik, anticorps Nos-3, anticorps ecNOS, anticorps EC-NOS, anticorps NOSIII, anticorps cNOS, anticorps NOS, anticorps NOS3, anticorps eNos, anticorps ENOS, anticorps nitric oxide synthase 3, anticorps nitric oxide synthase 3, endothelial cell, anticorps NOS3, anticorps Nos3, anticorps nos3

Sujet:

Synonyms: eNOS, ECNOS, Nitric oxide synthase, endothelial, Constitutive NOS, cNOS, EC-NOS, Endothelial NOS, NOS type III, NOSIII, NOS3

Background: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.

ID gène: 4846

UniProt: P29474

Pathways: ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling