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CRTC1 anticorps (pSer151) (FITC)

CRTC1 Reactivité: Humain, Poulet WB, IF (p), IF (cc) Hôte: Lapin Polyclonal FITC
N° du produit ABIN746565
  • Antigène Voir toutes CRTC1 Anticorps
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    Épitope
    • 21
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    pSer151
    Reactivité
    • 67
    • 37
    • 25
    • 14
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Poulet
    Hôte
    • 55
    • 13
    • 1
    Lapin
    Clonalité
    • 55
    • 14
    Polyclonal
    Conjugué
    • 33
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CRTC1 est conjugé à/à la FITC
    Application
    • 52
    • 24
    • 20
    • 12
    • 9
    • 8
    • 8
    • 7
    • 6
    • 6
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Specificité
    Due to the highly conserved nature of this protein, this antibody will react with Torc3 when phosphorylated at Ser162 across the listed species due to homology.
     Réactivité croisée
    Poulet, Humain
    Homologie
    Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic phosphopeptide derived from human Torc1 around the phosphorylation site of Ser151
    Isotype
    IgG
    Top Product
    Discover our top product CRTC1 Anticorps primaire
  • Indications d'application
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))
    Autre désignation
    Torc1 (CRTC1 Produits)
    Synonymes
    anticorps MECT1, anticorps TORC-1, anticorps TORC1, anticorps WAMTP1, anticorps AI413414, anticorps Mect1, anticorps R74955, anticorps mKIAA0616, anticorps CRTC1, anticorps crtc1, anticorps fc68c05, anticorps pde4cb, anticorps si:ch211-255d18.1, anticorps si:ch211-255d18.8, anticorps wu:fc68c05, anticorps CREB regulated transcription coactivator 1, anticorps CREB regulated transcription coactivator 1b, anticorps CRTC1, anticorps Crtc1, anticorps crtc1, anticorps crtc1b
    Sujet

    Synonyms: MECT1, TORC1, TORC-1, WAMTP1, CREB-regulated transcription coactivator 1, Mucoepidermoid carcinoma translocated protein 1, Transducer of regulated cAMP response element-binding protein 1, Transducer of CREB protein 1, CRTC1, KIAA0616

    Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.

    ID gène
    23373
    UniProt
    Q6UUV9
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