WEE1 anticorps (pSer642)
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- Antigène Voir toutes WEE1 Anticorps
- WEE1 (WEE1 Homolog (S. Pombe) (WEE1))
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Épitope
- pSer642
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp WEE1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Mouse,Rat,Dog,Cow,Pig,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from human Wee1 around the phosphorylation site of Ser642 [SV(p-S)LT]
- Isotype
- IgG
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anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer123) antibody
WEE1 Reactivité: Souris WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer123) antibodyWEE1 Reactivité: Humain IHC (p), DB Hôte: Lapin Polyclonal RB07865 unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 289-388) antibodyWEE1 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 5B6 unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 144-173) antibodyWEE1 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB3524 unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 604-634), (C-Term) antibodyWEE1 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB3525 unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 1-646) antibodyWEE1 Reactivité: Humain WB, PLA Hôte: Lapin Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 1-646) antibodyWEE1 Reactivité: Humain WB, IF Hôte: Souris Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (AA 604-634) antibodyWEE1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer123) antibodyWEE1 Reactivité: Humain ELISA, IHC, DB Hôte: Lapin Polyclonal unconjugated
anti-WEE1 Homolog (S. Pombe) (WEE1) (pSer642) antibodyWEE1 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- WEE1 (WEE1 Homolog (S. Pombe) (WEE1))
- Autre désignation
- Wee1 (WEE1 Produits)
- Sujet
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Synonyms: WEE1A, WEE1hu, Wee1-like protein kinase, Wee1A kinase, WEE1
Background: Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation.
- ID gène
- 7465
- UniProt
- P30291
- Pathways
- Cycle Cellulaire, Mitotic G1-G1/S Phases, M Phase
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