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Id2 anticorps (AA 31-134) (Biotin)

Id2 Reactivité: Rat ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN747475
  • Antigène Voir toutes Id2 Anticorps
    Id2 (Inhibitor of DNA Binding 2 (Id2))
    Épitope
    • 14
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-134
    Reactivité
    • 34
    • 30
    • 14
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 40
    • 8
    • 1
    Lapin
    Clonalité
    • 42
    • 7
    Polyclonal
    Conjugué
    • 23
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Id2 est conjugé à/à la Biotin
    Application
    • 21
    • 17
    • 13
    • 13
    • 9
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    Due to the similarity of this protein with ID1, this antibody has a chance to have light cross-reactivity with ID1 due to a 77 % sequence similarity in the range of our immunogen.
     Réactivité croisée
    Rat
    Homologie
    Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human GIG8/ID2
    Isotype
    IgG
    Top Product
    Discover our top product Id2 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    Id2 (Inhibitor of DNA Binding 2 (Id2))
    Autre désignation
    ID2 (Id2 Produits)
    Synonymes
    anticorps AI255428, anticorps C78922, anticorps Idb2, anticorps bHLHb26, anticorps Ac2-300, anticorps GIG8, anticorps ID2A, anticorps ID2H, anticorps XId2, anticorps id2-A, anticorps inhibitor of DNA binding 2, anticorps inhibitor of DNA binding 2, HLH protein, anticorps inhibitor of DNA binding 2 L homeolog, anticorps Id2, anticorps ID2, anticorps id2.L
    Sujet

    Synonyms: GIG8, ID2A, ID2H, bHLHb26, DNA-binding protein inhibitor ID-2, Class B basic helix-loop-helix protein 26, Inhibitor of DNA binding 2, Inhibitor of differentiation 2, ID2

    Background: Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism.

    ID gène
    3398
    UniProt
    Q02363
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