MLXIPL anticorps (AA 81-180) (Biotin)

N° du produit ABIN747490

Détail du produit anti-MLXIPL anticorps (Biotin)

Antigène: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Épitope: AA 81-180

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLXIPL est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human WBSCR14/ChREBP

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur MLXIPL

Antigène: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Autre désignation: WBSCR14 (MLXIPL Produits)

Synonymes: anticorps ChREBP, anticorps MLXIPL, anticorps CHREBP, anticorps MIO, anticorps MONDOB, anticorps WBSCR14, anticorps WS-bHLH, anticorps bHLHd14, anticorps Wbscr14, anticorps MLX interacting protein-like, anticorps MLX interacting protein like, anticorps MLXIPL, anticorps Mlxipl

Sujet:

Synonyms: ChREBP, bHLHd14, Carbohydrate responsive element binding protein, MIO, MLX interacting protein like, Mlx interactor, MLXIPL, MONDOB, WBSCR 14, WBSCR14, Williams Beuren syndrome chromosome region 14, Williams Beuren syndrome chromosome region 14 protein, WS basic helix loop helix leucine zipper protein, WS bHLH, MLXPL_HUMAN.

Background: ChREBP (Carbohydrate responsive element binding protein) is a transcription factor playing a critical role in the nutrient and hormonal regulation of genes encoding enzymes of glucose metabolism and lipogenesis pathways. It contains several domains including a nuclear localization signal (NLS) near the N-terminus, polyproline domains, a basic helix-loop-helix leucine zipper (b/HLH/Zip) and a leucine zipper like (zip-like) domain.ChREBP is ubiquitously detected in various tissues, with highest expression in liver, kidney and white and brown adipose tissue. Under basal conditions ChREBP is localized in the cytosol, translocating into the nucleus upon high glucose stimulation following its dephosphorylation of serine 196.

ID gène: 51085

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process