IL5RA anticorps (AA 11-110) (Biotin)

N° du produit ABIN747835

Détail du produit anti-IL5RA anticorps (Biotin)

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Épitope: AA 11-110

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL5RA est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IL-5R alpha

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur IL5RA

Antigène: IL5RA (Interleukin 5 Receptor, alpha (IL5RA))

Autre désignation: IL5RA/CD125 (IL5RA Produits)

Synonymes: anticorps MGC86517, anticorps IL5RA, anticorps il5r, anticorps cdw125, anticorps hsil5r3, anticorps gpIL-5ra, anticorps CD125, anticorps CDw125, anticorps HSIL5R3, anticorps IL5R, anticorps Il5r, anticorps interleukin 5 receptor subunit alpha L homeolog, anticorps interleukin 5 receptor subunit alpha, anticorps interleukin 5 receptor, alpha, anticorps il5ra.L, anticorps IL5RA, anticorps il5ra, anticorps Il5ra

Sujet:

Synonyms: Interleukin-5 receptor alpha, CD125 antigen, CDw125, HSIL5R3, IL5R, IL-5R, Interleukin 5 Receptor alpha, Interleukin 5 receptor subunit alpha, interleukin 5 receptor type 3, MGC26560, IL5RA, IL-5R alpha, IL5RA_HUMAN.

Background: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3(IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5(IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.

ID gène: 3568

UniProt: Q01344

Pathways: Signalistation JAK/STAT