IL10RB anticorps (AA 21-120)

N° du produit ABIN747848

Détail du produit anti-IL10RB anticorps

Antigène: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Épitope: AA 21-120

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL10RB est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IL10RB

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-IL10RB (ABIN747848)

Lopušná, Benkóczka, Lupták, Matúšková, Lukáčiková, Ovečková, Režuchová: "Murine gammaherpesvirus targets type I IFN receptor but not type III IFN receptor early in infection." dans: Cytokine, Vol. 83, pp. 158-70, (2016) (PubMed).

Ohnuma, Hatano, Aune, Otsuka, Iwata, Dang, Yamada, Morimoto: "Regulation of pulmonary graft-versus-host disease by IL-26+CD26+CD4 T lymphocytes." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 8, pp. 3697-712, (2015) (PubMed).

Détails sur IL10RB

Antigène: IL10RB (Interleukin 10 Receptor, beta (IL10RB))

Autre désignation: IL10RB (IL10RB Produits)

Synonymes: anticorps IL10R2, anticorps IL10RB, anticorps il10r2, anticorps CDW210B, anticorps CRF2-4, anticorps CRFB4, anticorps D21S58, anticorps D21S66, anticorps IL-10R2, anticorps 6620401D04Rik, anticorps AI528744, anticorps Crfb4, anticorps D16H21S58, anticorps D21S58h, anticorps Il10r2, anticorps RGD1560373, anticorps interleukin 10 receptor subunit beta, anticorps interleukin 10 receptor subunit beta S homeolog, anticorps interleukin-10 receptor subunit beta, anticorps interleukin 10 receptor, beta, anticorps IL10RB, anticorps il10rb.S, anticorps LOC473966, anticorps LOC478404, anticorps il10rb, anticorps Il10rb

Sujet:

Synonyms: Interleukin-10 receptor subunit beta, IL-10 receptor subunit beta, IL-10R subunit beta, IL-10RB, Cytokine receptor class-II member 4, Cytokine receptor family 2 member 4, CRF2-4, Interleukin-10 receptor subunit 2, IL-10R subunit 2, IL-10R2, CDw210b, IL10RB, CRFB4, D21S58, D21S66

Background: Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state.

ID gène: 3588

UniProt: Q08334