IL15RA anticorps (AA 51-150)

N° du produit ABIN747893

Détail du produit anti-IL15RA anticorps

Antigène: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Épitope: AA 51-150

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL15RA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human IL-15RA

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-IL15RA (ABIN747893)

Yoon, Johnson, Xu, Martin, Martin, Montanaro: "Comparative proteomic profiling of dystroglycan-associated proteins in wild type, mdx, and Galgt2 transgenic mouse skeletal muscle." dans: Journal of proteome research, Vol. 11, Issue 9, pp. 4413-24, (2012) (PubMed).

Détails sur IL15RA

Antigène: IL15RA (Interleukin 15 Receptor, alpha (IL15RA))

Autre désignation: IL-15RA (IL15RA Produits)

Synonymes: anticorps IL15RA, anticorps CD215, anticorps AA690181, anticorps IL-15RA, anticorps interleukin 15 receptor subunit alpha, anticorps interleukin 15 receptor, alpha chain, anticorps IL15RA, anticorps Il15ra

Sujet:

Synonyms: Interleukin-15 receptor subunit alpha, IL 15R alpha, IL15RA, Interleukin 15 receptor alpha, Interleukin 15 receptor subunit alpha, Soluble interleukin 15 receptor subunit alpha, I15RA_HUMAN.

Background: IL15RA is a cytokine receptor that specifically binds IL15 with high affinity. It shares two subunits with the receptor of IL2, the IL2R beta and IL2R gamma chains. This forms the basis of many overlapping biological activities of IL15 and IL2. The IL2 receptor requires an additional IL2-specific alpha subunit for high affinity IL2 binding. This protein is structurally related to IL2R alpha, but is capable of binding IL15 with high affinity independent of other subunits, which suggests the distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. There are nine different isoforms.

ID gène: 3601

Pathways: Signalistation JAK/STAT