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IL-33 anticorps (AA 185-264)

IL33 Reactivité: Souris, Rat ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN748313
  • Antigène Voir toutes IL-33 (IL33) Anticorps
    IL-33 (IL33) (Interleukin 33 (IL33))
    Épitope
    • 22
    • 15
    • 10
    • 9
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 185-264
    Reactivité
    • 86
    • 47
    • 37
    • 9
    • 1
    Souris, Rat
    Hôte
    • 104
    • 28
    • 8
    • 2
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 115
    • 31
    Polyclonal
    Conjugué
    • 74
    • 23
    • 13
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL-33 est non-conjugé
    Application
    • 89
    • 70
    • 37
    • 27
    • 18
    • 14
    • 13
    • 13
    • 12
    • 12
    • 9
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from mouse IL-33
    Isotype
    IgG
    Top Product
    Discover our top product IL33 Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Chen, Qu, Li, Ye, Zhang, Qin, Fan: "Effects of 1,25-dihydroxyvitamin D3 in an ovalbumin-induced allergic rhinitis model." dans: International immunopharmacology, Vol. 47, pp. 182-189, (2017) (PubMed).

    Demirtas, Turkmen, Kandemir, Ozkaraca, Kucukler, Gürbüzel, Comaklı: "The possible role of interleukin-33 as a new player in the pathogenesis of contrast-induced nephropathy in diabetic rats." dans: Renal failure, pp. 1-9, (2016) (PubMed).

  • Antigène
    IL-33 (IL33) (Interleukin 33 (IL33))
    Autre désignation
    IL-33 (IL33 Produits)
    Synonymes
    anticorps IL33, anticorps C9orf26, anticorps DVS27, anticorps IL1F11, anticorps NF-HEV, anticorps NFEHEV, anticorps RP11-575C20.2, anticorps 9230117N10Rik, anticorps Il-33, anticorps Il1f11, anticorps RGD1311155, anticorps interleukin 33, anticorps IL33, anticorps Il33
    Sujet

    Synonyms: Il-33, Il1f11, NF-HEV, 9230117N10Rik, Interleukin-33, Il33

    Background: Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells. Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury. In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB/RELA, lowering expression of its targets. This form is rapidely lost upon angiogenic or proinflammatory activation.

    ID gène
    77125
    UniProt
    Q8BVZ5
    Pathways
    Production of Molecular Mediator of Immune Response
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