LAG3 anticorps (AA 210-260) (PE)
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- Antigène Voir toutes LAG3 Anticorps
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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Épitope
- AA 210-260
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LAG3 est conjugé à/à la PE
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Application
- Western Blotting (WB)
- Réactivité croisée
- Humain, Souris
- Homologie
- Rat,Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Lymphocyte Activation Gene 3
- Isotype
- IgG
- Top Product
- Discover our top product LAG3 Anticorps primaire
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- Indications d'application
- FCM(1:20-100)
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes." dans: Cancer immunology, immunotherapy : CII, Vol. 62, Issue 5, pp. 851-62, (2013) (PubMed).
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CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes." dans: Cancer immunology, immunotherapy : CII, Vol. 62, Issue 5, pp. 851-62, (2013) (PubMed).
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- Antigène
- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
- Autre désignation
- Lymphocyte Activation Gene 3 (LAG3 Produits)
- Synonymes
- anticorps CD223, anticorps LAG-3, anticorps Ly66, anticorps lymphocyte activating 3, anticorps lymphocyte-activation gene 3, anticorps LAG3, anticorps Lag3
- Sujet
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Synonyms: CD223, Lymphocyte activation gene 3 protein, LAG-3, Lag3
Background: Lymphocyte-activation protein 3 (LAG-3), also known as CD223, belongs to the immunoglobulin superfamily and contains 4 extracellular Ig-like domains. LAG-3 binds to HLA class-II antigens and is involved in lymphocyte activation. It is found on the cell surface of activated NK and T-lymphocytes. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG-3 to CD4.
- ID gène
- 297596
- UniProt
- Q5BK54
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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