SPHK2 anticorps (AA 101-200)

N° du produit ABIN748613

Détail du produit anti-SPHK2 anticorps

Antigène: SPHK2 (Sphingosine Kinase 2 (SPHK2))

Épitope: AA 101-200

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPHK2 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SPHK2

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-SPHK2 (ABIN748613)

Tran, Jersmann, Truong, Hamon, Roscioli, Ween, Pitman, Pitson, Hodge, Reynolds, Hodge: "Disrupted epithelial/macrophage crosstalk via Spinster homologue 2-mediated S1P signaling may drive defective macrophage phagocytic function in COPD." dans: PLoS ONE, Vol. 12, Issue 11, pp. e0179577, (2017) (PubMed).

Zhang, Li, Yuan, Zhao: "Hypoxic preconditioning protects cardiomyocytes against hypoxia/reoxygenation-induced cell apoptosis via sphingosine kinase 2 and FAK/AKT pathway." dans: Experimental and molecular pathology, Vol. 100, Issue 1, pp. 51-8, (2016) (PubMed).

Tani, Tabuchi, Hara: "Hair Cell Loss Induced by Sphingosine and a Sphingosine Kinase Inhibitor in the Rat Cochlea." dans: Neurotoxicity research, Vol. 29, Issue 1, pp. 35-46, (2016) (PubMed).

Tran, Barnawi, Ween, Hamon, Roscioli, Hodge, Reynolds, Pitson, Davies, Haberberger, Hodge: "Cigarette smoke inhibits efferocytosis via deregulation of sphingosine kinase signaling: reversal with exogenous S1P and the S1P analogue FTY720." dans: Journal of leukocyte biology, Vol. 100, Issue 1, pp. 195-202, (2016) (PubMed).

Détails sur SPHK2

Antigène: SPHK2 (Sphingosine Kinase 2 (SPHK2))

Autre désignation: SPHK2 (SPHK2 Produits)

Synonymes: anticorps CG2159, anticorps CG32484, anticorps Dmel\\CG32484, anticorps SK2, anticorps Sphk2, anticorps sk2, anticorps DKFZp469F224, anticorps SK 2, anticorps SK-2, anticorps SPK 2, anticorps SPK-2, anticorps C76851, anticorps Sphingosine kinase, anticorps sphk2, anticorps Sphingosine kinase 2, anticorps sphingosine kinase 2, anticorps sphK2, anticorps Sk2, anticorps SPHK2, anticorps Sphk2

Sujet:

Synonyms: SK 2, SK-2, SPK 2, SPK-2, Sphingosine kinase 2, SPHK2

Background: Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides.

ID gène: 56848

UniProt: Q9NRA0

Pathways: VEGF Signaling