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NFAM1 anticorps (AA 81-180)

NFAM1 Reactivité: Humain, Souris, Rat WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN749033
  • Antigène Voir toutes NFAM1 Anticorps
    NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))
    Épitope
    • 14
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 81-180
    Reactivité
    • 34
    • 17
    • 17
    • 3
    Humain, Souris, Rat
    Hôte
    • 31
    • 3
    Lapin
    Clonalité
    • 33
    • 1
    Polyclonal
    Conjugué
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NFAM1 est non-conjugé
    Application
    • 23
    • 12
    • 12
    • 8
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Pig,Horse
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human NFAM1
    Isotype
    IgG
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Sambandam, Sundaram, Saigusa, Balasubramanian, Reddy: "NFAM1 signaling enhances osteoclast formation and bone resorption activity in Paget's disease of bone." dans: Bone, Vol. 101, pp. 236-244, (2018) (PubMed).

  • Antigène
    NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))
    Autre désignation
    NFAM1 (NFAM1 Produits)
    Synonymes
    anticorps 4921501M20Rik, anticorps Cnaip, anticorps CNAIP, anticorps bK126B4.4, anticorps RGD1308316, anticorps NFAT activating protein with ITAM motif 1, anticorps Nfat activating molecule with ITAM motif 1, anticorps NFAM1, anticorps Nfam1
    Sujet

    Synonyms: CNAIP, bK126B4.4, NFAT activation molecule 1, Calcineurin/NFAT-activating ITAM-containing protein, NFAT-activating protein with ITAM motif 1, NFAM1

    Background: May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.

    ID gène
    150372
    UniProt
    Q8NET5
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