NFAM1 anticorps (AA 81-180)
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- Antigène Voir toutes NFAM1 Anticorps
- NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))
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Épitope
- AA 81-180
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NFAM1 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human NFAM1
- Isotype
- IgG
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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NFAM1 signaling enhances osteoclast formation and bone resorption activity in Paget's disease of bone." dans: Bone, Vol. 101, pp. 236-244, (2018) (PubMed).
: "
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NFAM1 signaling enhances osteoclast formation and bone resorption activity in Paget's disease of bone." dans: Bone, Vol. 101, pp. 236-244, (2018) (PubMed).
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- Antigène
- NFAM1 (NFAT Activating Protein with ITAM Motif 1 (NFAM1))
- Autre désignation
- NFAM1 (NFAM1 Produits)
- Synonymes
- anticorps 4921501M20Rik, anticorps Cnaip, anticorps CNAIP, anticorps bK126B4.4, anticorps RGD1308316, anticorps NFAT activating protein with ITAM motif 1, anticorps Nfat activating molecule with ITAM motif 1, anticorps NFAM1, anticorps Nfam1
- Sujet
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Synonyms: CNAIP, bK126B4.4, NFAT activation molecule 1, Calcineurin/NFAT-activating ITAM-containing protein, NFAT-activating protein with ITAM motif 1, NFAM1
Background: May function in immune system as a receptor which activates via the calcineurin/NFAT-signaling pathway the downstream cytokine gene promoters. Activates the transcription of IL-13 and TNF-alpha promoters. May be involved in the regulation of B-cell, but not T-cell, development. Overexpression activates downstream effectors without ligand binding or antibody cross-linking.
- ID gène
- 150372
- UniProt
- Q8NET5
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