DKK3 anticorps (AA 31-130)

N° du produit ABIN749123

Détail du produit anti-DKK3 anticorps

Antigène: DKK3

Épitope: AA 31-130

Reactivité: Souris, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DKK3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Lapin

Homologie: Human,Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human DKK3

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur DKK3

Antigène: DKK3

Abstract: DKK3 Produits

Synonymes: anticorps REIC, anticorps RIG, anticorps reic, anticorps dkk-3, anticorps AW061014, anticorps C87148, anticorps Reic, anticorps p29, anticorps dickkopf WNT signaling pathway inhibitor 3, anticorps dickkopf WNT signaling pathway inhibitor 3 S homeolog, anticorps DKK3, anticorps dkk3, anticorps dkk3.S, anticorps Dkk3

Sujet:

Synonyms: RIG, REIC, Dickkopf-related protein 3, Dickkopf-3, Dkk-3, hDkk-3, DKK3, UNQ258/PRO295

Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

ID gène: 27122

UniProt: Q9UBP4