MCM5 anticorps (AA 651-734)

N° du produit ABIN749648

Détail du produit anti-MCM5 anticorps

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Épitope: AA 651-734

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MCM5

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur MCM5

Antigène: MCM5 (Minichromosome Maintenance Complex Component 5 (MCM5))

Autre désignation: MCM5 (MCM5 Produits)

Synonymes: anticorps 23.m06024, anticorps cdc46, anticorps xmcm5, anticorps CDC46, anticorps P1-CDC46, anticorps Afu5g02520, anticorps NCU01171.1, anticorps AA617332, anticorps AI324988, anticorps AL033333, anticorps Cdc46, anticorps Mcmd5, anticorps mCD46, anticorps mCDC46, anticorps mcm5, anticorps wu:fb34a06, anticorps CG4082, anticorps DmCDC46, anticorps DmCDC465, anticorps DmMCM5, anticorps DmMcm5, anticorps DmeMCM5, anticorps Dmel\\CG4082, anticorps MCM5, anticorps McM5, anticorps PCR4, anticorps DNA replication licensing factor MCM5, anticorps minichromosome maintenance complex component 5 S homeolog, anticorps minichromosome maintenance complex component 5, anticorps DNA replication licensing factor Mcm5, anticorps DNA replication licensing factor mcm5, anticorps MCM5 minichromosome maintenance deficient 5 (S. cerevisiae), anticorps minichromosome maintenance complex component 5 L homeolog, anticorps Minichromosome maintenance 5, anticorps DNA replication licensing factor mcm-5, anticorps BBOV_IV010040, anticorps mcm5.S, anticorps MCM5, anticorps AFUA_5G02520, anticorps NCU01171, anticorps PVX_084615, anticorps LOC5576119, anticorps CpipJ_CPIJ008678, anticorps Bm1_24480, anticorps CMU_022890, anticorps Mcm5, anticorps mcm5, anticorps TP01_0722, anticorps mcm5.L, anticorps mcm-5

Sujet:

Synonyms: CDC46, P1-CDC46, DNA replication licensing factor MCM5, CDC46 homolog, MCM5

Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity). Interacts with MCMBP.

ID gène: 4174

UniProt: P33992

Pathways: Réparation de l'ADN, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA