TREM2 anticorps (AA 1-100)

N° du produit ABIN749678

Détail du produit anti-TREM2 anticorps

Antigène: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Épitope: AA 1-100

Reactivité: Souris, Humain, Rat, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TREM2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Porc, Rat

Homologie: Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TREM2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-TREM2 (ABIN749678)

Abdi, Pasbakhsh, Shabani, Nekoonam, Sadeghi, Fathi, Abouzaripour, Mohamed, Zibara, Kashani, Zendedel: "Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis." dans: Neurotoxicity research, (2021) (PubMed).

Rai, Dietz, Dilisio, Radwan, Agrawal: "Vitamin D attenuates inflammation, fatty infiltration, and cartilage loss in the knee of hyperlipidemic microswine." dans: Arthritis research & therapy, Vol. 18, Issue 1, pp. 203, (2016) (PubMed).

Satoh, Kawana, Yamamoto, Ishida, Saito, Arima: "A survey of TREM2 antibodies reveals neuronal but not microglial staining in formalin-fixed paraffin-embedded postmortem Alzheimer's brain tissues." dans: Alzheimer's research & therapy, Vol. 5, Issue 4, pp. 30, (2014) (PubMed).

Détails sur TREM2

Antigène: TREM2 (Triggering Receptor Expressed On Myeloid Cells 2 (TREM2))

Autre désignation: TREM2 (TREM2 Produits)

Synonymes: anticorps TREM-A1, anticorps TREM-B1, anticorps TREM2, anticorps trem-2, anticorps trem2a, anticorps trem2b, anticorps trem2c, anticorps TREM-2, anticorps Trem2a, anticorps Trem2b, anticorps Trem2c, anticorps triggering receptor expressed on myeloid cells 2, anticorps trem-like transcript 2 protein, anticorps TREM2, anticorps trem2, anticorps LOC100228399, anticorps Trem2

Sujet:

Synonyms: TREM-2, Trem2a, Trem2b, Trem2c, Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on monocytes 2, TREM2

Background: May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.

ID gène: 54209

UniProt: Q9NZC2