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CRLF2 anticorps (AA 81-180) (Biotin)

CRLF2 Reactivité: Humain ELISA, IHC (p), IHC (fro) Hôte: Lapin Polyclonal Biotin
N° du produit ABIN749740
  • Antigène Voir toutes CRLF2 Anticorps
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    Épitope
    • 14
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-180
    Reactivité
    • 44
    • 24
    • 19
    Humain
    Hôte
    • 47
    • 18
    • 3
    Lapin
    Clonalité
    • 50
    • 18
    Polyclonal
    Conjugué
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CRLF2 est conjugé à/à la Biotin
    Application
    • 37
    • 26
    • 26
    • 14
    • 10
    • 8
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human CRLF2
    Isotype
    IgG
    Top Product
    Discover our top product CRLF2 Anticorps primaire
  • Indications d'application
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C for 12 months.
    Date de péremption
    12 months
  • Antigène
    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
    Autre désignation
    Crlf2 (CRLF2 Produits)
    Synonymes
    anticorps CRLF2, anticorps CRL2, anticorps CRLF2Y, anticorps TSLPR, anticorps CRLM2, anticorps Ly114, anticorps Tpte2, anticorps Tslpr, anticorps Crl2, anticorps cytokine receptor like factor 2, anticorps cytokine receptor-like factor 2, anticorps CRLF2, anticorps Crlf2
    Sujet

    Synonyms: TSLPR, CRLF2, CRL 2, CRL2, CRLF 2, CRLF2Y, Cytokine receptor CRL2 precusor, Cytokine receptor like 2, Cytokine receptor like factor 2, Cytokine receptor like factor 2 precursor, IL XR, ILXR, Thymic stromal derived lymphopoietin receptor, Thymic stromal lymphopoietin protein receptor, Thymic stromal lymphopoietin receptor, TSLP receptor, TSLPR.

    Background: TSLPR is a type I membrane receptor that forms a functional heterodimeric complex with IL7R to bind TSLP. The TSLP R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs. TSLPR has a predicted molecular weight approximately 41 kD, and two further isoforms have been reported that are produced by alternative splicing. The TSLPR is expressed preferentially in myeloid cells including dendritic cells and activated monocytes, and is weakly expressed in T cells. Expression has also been reported in heart, skeletal muscle, and kidney tissues. TSLP binding to the heterodimeric functional receptor (TSLPR and IL7R) activates JAK2, STAT3 and STAT5 to stimulate cell proliferation. Ligand receptor interactions haves been implicated in the development of the hematopoietic system, dendritic cell maturation, and the maintenance and polarization of human Th2 memory T cells in allergic diseases.

    ID gène
    64109
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