LGMN anticorps (AA 201-300)
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- Antigène Voir toutes LGMN Anticorps
- LGMN (Legumain (LGMN))
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Épitope
- AA 201-300
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp LGMN est non-conjugé
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Application
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Humain, Souris, Rat
- Homologie
- Dog,Cow,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Legumain
- Isotype
- IgG
- Top Product
- Discover our top product LGMN Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- LGMN (Legumain (LGMN))
- Autre désignation
- Legumain (LGMN Produits)
- Synonymes
- anticorps AEP, anticorps LGMN1, anticorps PRSC1, anticorps AI746452, anticorps AU022324, anticorps Prsc1, anticorps MGC64351, anticorps cb173, anticorps cb460, anticorps sb:cb173, anticorps zgc:76953, anticorps wu:fa98g05, anticorps wu:fj92g08, anticorps lgmn, anticorps MGC88980, anticorps DELTA VACUOLAR PROCESSING ENZYME, anticorps DELTAVPE, anticorps delta vacuolar processing enzyme, anticorps legumain, anticorps legumain L homeolog, anticorps delta vacuolar processing enzyme, anticorps Legumain, anticorps LGMN, anticorps Lgmn, anticorps lgmn.L, anticorps lgmn, anticorps DELTA-VPE, anticorps MBOO_RS07785, anticorps Odosp_3582, anticorps LOC569153
- Sujet
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Synonyms: AEP, LGMN1, PRSC1, Legumain, Asparaginyl endopeptidase, Protease, cysteine 1, LGMN
Background: Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR. Plays a role in the regulation of cell proliferation via its role in EGFR degradation (By similarity). May be involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system.
- ID gène
- 5641
- UniProt
- Q99538
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Activation of Innate immune Response, Toll-Like Receptors Cascades
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