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ATG12 anticorps (AA 101-187)

Name: ATG12 anticorps (AA 101-187)
SKU: ABIN752518
Price: 384.62 EUR
Availability: InStock

ATG12 Reactivité: Souris, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

Formalin-fixed and paraffin embedded mouse Kidney tissue labeled with Anti Apg12 Polyclonal Antibody, unconjugated (ABIN752518) at 1:200 followed by incubation with conjugated secondary antibody and DAB staining. (ATG12 anticorps (AA 101-187))

IHC

Formalin-fixed and paraffin embedded mouse embryo tissue labeled with Anti Apg12 Polyclonal Antibody,Unconjugated (ABIN752518) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (ATG12 anticorps (AA 101-187))

IHC

Formalin-fixed and paraffin embedded rat lung labeled with Rabbit Anti-Apg12 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (ATG12 anticorps (AA 101-187))

IHC (p)

3 images

(1 reference)

N° du produit ABIN752518

Fiche de données

Antigène Voir toutes ATG12 Anticorps

ATG12 (Autophagy Related 12 (ATG12))
Épitope
14

13

8

7

6

6

6

3

2

2

2

1

1

1

1

1

1

1

1
AA 101-187
Reactivité
79

35

25

6

6

6

6

5

4

4

4

4

2

2

2

2

2

2

2

2

1
Souris, Rat
Hôte
75

19

2
Lapin
Anticorps secondaires appropriés
Clonalité
73

23
Polyclonal
Conjugué
48

7

6

6

6

4

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Cet anticorp ATG12 est non-conjugé
Application
73

40

30

28

21

12

12

9

8

3

2

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée

Souris, Rat

Homologie

Human,Dog,Cow,Pig,Rabbit

Purification

Purified by Protein A.

Immunogène

KLH conjugated synthetic peptide derived from human ATG12

Isotype

IgG

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ATG12 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated

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ATG12 Reactivité: Humain WB, IHC, IP Hôte: Lapin Monoclonal unconjugated

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ATG12 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1F9 unconjugated

anti-Autophagy Related 12 (ATG12) (AA 1-74) antibody
ATG12 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 2H8 unconjugated

Indications d'application

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur

ProClin

Précaution d'utilisation

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock

4 °C,-20 °C

Stockage commentaire

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption

12 months
Song, Kou, Zou, Gao, Zeng, Xie: "Involvement of autophagy in tri-ortho-cresyl phosphate- induced delayed neuropathy in hens." dans: Neurochemistry international, Vol. 64, pp. 1-8, (2013) (PubMed).
Antigène

ATG12 (Autophagy Related 12 (ATG12))

Autre désignation

Apg12 (ATG12 Produits)

Sujet

Synonyms: APG12, FBR93, APG12L, HAPG12, Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like, ATG12
Background: Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG1 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus.

ID gène

9140

UniProt

O94817

Pathways

Autophagy