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G6PC anticorps (Cy5)

G6PC Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Porc WB, IF (p) Hôte: Lapin Polyclonal Cy5
N° du produit ABIN753002
  • Antigène Voir toutes G6PC Anticorps
    G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
    Reactivité
    • 42
    • 21
    • 20
    • 15
    • 13
    • 12
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Chien, Boeuf (Vache), Porc
    Hôte
    • 42
    • 1
    Lapin
    Clonalité
    • 42
    • 1
    Polyclonal
    Conjugué
    • 12
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp G6PC est conjugé à/à la Cy5
    Application
    • 30
    • 19
    • 15
    • 11
    • 10
    • 4
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
     Réactivité croisée
    Boeuf (Vache), Chien, Humain, Souris, Porc, Rat
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human Glucose 6 phosphatase alpha
    Isotype
    IgG
    Top Product
    Discover our top product G6PC Anticorps primaire
  • Indications d'application
    IF(IHC-P)(1:100-500)
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    G6PC (Glucose 6-Phosphatase, Catalytic (G6PC))
    Autre désignation
    Glucose 6 phosphatase alpha (G6PC Produits)
    Synonymes
    anticorps AW107337, anticorps G6Pase, anticorps G6pt, anticorps Glc-6-Pase, anticorps G6PC1, anticorps G6PT, anticorps GSD1, anticorps GSD1a, anticorps G-6-Pase, anticorps glucose-6-phosphatase, catalytic, anticorps glucose-6-phosphatase catalytic subunit, anticorps glucose-6-phosphatase, catalytic subunit, anticorps G6pc, anticorps G6PC
    Sujet

    Synonyms: glucose-6-phosphatase, catalytic subunit, GSD1, AW107337, G-6-Pase, G6Pase, G6Pase-alpha, g6pc, G6PC_HUMAN, G6PT, Glucose-6-phosphatase alpha, Glucose-6-phosphatase, GSD1a, MGC163350, MGC93613, RP23-281C18.19.

    Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-i±, a second form, designated G6Pase-i², contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-i², also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-i² hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-i² may play an integral role in diabetes and glycogen storage diseases (GSDs).

    Poids moléculaire
    40kDa
    ID gène
    2538
    Pathways
    Carbohydrate Homeostasis, Cellular Glucan Metabolic Process
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