HMGCR anticorps (pSer872)

N° du produit ABIN753283

Détail du produit anti-HMGCR anticorps

Antigène: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Épitope: pSer872

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HMGCR est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This phosphorylation site is homologous to that of Ser871 in Mouse and Rat.

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human HMGCR around the phosphorylation site of Ser872

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-HMGCR (ABIN753283)

Zanoni, Aiello, Arnoldi, Lammi: "Hempseed Peptides Exert Hypocholesterolemic Effects with a Statin-Like Mechanism." dans: Journal of agricultural and food chemistry, Vol. 65, Issue 40, pp. 8829-8838, (2017) (PubMed).

Yang, Ouyang, Chen, Pang, Dong, Yang, Liu, Peng, Wang, Zhang, Ren: "HMG-CoA reductase is negatively associated with PCV2 infection and PCV2-induced apoptotic cell death." dans: The Journal of general virology, Vol. 95, Issue Pt 6, pp. 1330-7, (2014) (PubMed).

Détails sur HMGCR

Antigène: HMGCR (3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCR))

Autre désignation: HMGCR (HMGCR Produits)

Synonymes: anticorps HMGR, anticorps LDLCQ3, anticorps hmg-coa-r, anticorps HMG-CoAR, anticorps Red, anticorps 3H3M, anticorps BcDNA:LD15354, anticorps CG10367, anticorps Clb, anticorps DmHMG-CoAr, anticorps Dmel\\CG10367, anticorps HMGCR, anticorps HMGCR_Dm, anticorps HMGCoAR, anticorps HMGCoARr, anticorps HMGCoAr, anticorps HmG-CoAR, anticorps Hmg, anticorps bro1, anticorps bs32f05.y1, anticorps clb, anticorps hmgc, anticorps hmgcr, anticorps hmgrc, anticorps l(3)01152, anticorps l(3)04684, anticorps hmgcr2, anticorps im:6912716, anticorps zgc:110746, anticorps 3-hydroxy-3-methylglutaryl-CoA reductase, anticorps 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog, anticorps 3-hydroxy-3-methylglutaryl-Coenzyme A reductase, anticorps HMG Coenzyme A reductase, anticorps 3-hydroxy-3-methylglutaryl-CoA reductase b, anticorps HMGCR, anticorps hmgcr.L, anticorps Hmgcr, anticorps hmgcrb

Sujet:

Synonyms: LDLCQ3, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, HMG-CoA reductase, HMGCR, phospho HMGCR, p-HMGCR

Background: Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.

ID gène: 3156

UniProt: P04035

Pathways: AMPK Signaling, Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha